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Update on Endogenous Inhibitors of Angiogenesis
Endothelium, 2006Angiogenesis is regulated by a local balance between the levels of endogenous stimulators and inhibitors of angiogenesis. Understanding of the mechanism of angiogenesis has advanced significantly since the discovery of two members of the family of angiogenesis stimulators, i.e., vascular endothelial growth factor family proteins and angiopoietins ...
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The preclinical evaluation of angiogenesis inhibitors
Investigational New Drugs, 1997Angiogenesis is a fundamental process which is required for a number of physiological and pathophysiological processes. The field of angiogenesis therefore has many therapeutic implications and has progressed rapidly. Many strategies have been devised to regulate angiogenesis and several endogenous and synthetic inhibitors of angiogenesis have now been
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Inhibitors of Tumor Angiogenesis
2010Tumor growth relies on formation of a vascular supply. In 1971, Judah Folkman was the first to propose that in order to grow beyond 2–3 mm in size tumors required a new vascular network [16]. Subsequent research has confirmed that growth of a tumor, both at the primary site and metastases, is dependent on neoangiogenesis [17, 24]. This development of a
Anaadriana Zakarija +1 more
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Nanotechnology for angiogenesis: opportunities and challenges
Chemical Society Reviews, 2020Sepideh Hamzehlou +2 more
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Angiogenesis Inhibitors: Current Strategies and Future Prospects
Ca-A Cancer Journal for Clinicians, 2010Kristina M Cook, William D Figg
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Targeting vascular and leukocyte communication in angiogenesis, inflammation and fibrosis
Nature Reviews Drug Discovery, 2016Johan Kreuger, Mia Phillipson
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