Results 61 to 70 of about 3,183,533 (410)
Evaluation of Angiogenesis Inhibitors Using the HUVEC Fibrin Bead Sprouting Assay
Bio-Protocol, 2016 Angiogenesis, the growth of new blood vessels from pre-existing vessels, is a critical process that occurs during normal development and tumor formation.
Laura Winters +3 more
doaj +1 more source
The Angiogenic Balance and Its Implications in Cancer and Cardiovascular Diseases: An Overview
Medicina, 2022 Angiogenesis is the process of developing new blood vessels from pre-existing ones. This review summarizes the main features of physiological and pathological angiogenesis and those of angiogenesis activation and inhibition.
Cătălina Ionescu +7 more
doaj +1 more source
Angiogenesis inhibitors for the treatment of small cell lung cancer (SCLC)
Medicine, 2017 Background: This study aimed to assess the effectiveness and safety of angiogenesis inhibitors for the treatment of patients with small cell lung cancer (SCLC) via meta-analysis.
Qing Li +10 more
semanticscholar +1 more source
Temporal and spatial expression of tissue inhibitors of metalloproteinases 1 and 2 (TIMP-1 and -2) in the bovine corpus luteum [PDF]
, 2003 The matrix metalloproteinases (MMPs) and their endogenous inhibitors, tissue inhibitors of metalloproteinases (TIMPs), may mediate the dramatic structural and functional changes in the corpus luteum (CL) over the course of its life span.
Moses, Marsha A. +2 more
core +3 more sources
Vascular complications of cancer chemotherapy [PDF]
, 2015 Development of new anticancer drugs has resulted in improved mortality rates and 5-year survival rates in patients with cancer. However, many of the modern chemotherapies are associated with cardiovascular toxicities that increase cardiovascular risk in ...
Cameron, Alan C. +2 more
core +1 more source
Recent advances on anti-angiogenesis receptor tyrosine kinase inhibitors in cancer therapy
Journal of Hematology & Oncology, 2019 Angiogenesis has always been the topic of major scientific interest in the field of malignant tumors. Nowadays, targeting angiogenesis has achieved success in various carcinomas by several mechanisms, including the use of anti-angiogenic small molecule ...
Shuang Qin +5 more
semanticscholar +1 more source
Thyroid status modulates T lymphoma growth via cell cycle regulatory proteins and angiogenesis [PDF]
, 2014 We have shown in vitro that thyroid hormones (THs) regulate the balance between proliferation and apoptosis of T lymphoma cells. The effects of THs on tumor development have been studied, but the results are still controversial.
Barreiro Arcos, María Laura +10 more
core +1 more source
BMC Biotechnology, 2007 Background Angiogenesis assays are important tools for the identification of regulatory molecules and the potential development of therapeutic strategies to modulate neovascularization.
Desroches-Castan Agnès +5 more
doaj +1 more source
PDGFB as a vascular normalization agent in an ovarian cancer model treated with a gamma-secretase inhibitor [PDF]
, 2019 Ovarian cancer is the fifth leading cause of cancer-related deaths in women. In the past 20 years, the canonical types of drugs used to treat ovarian cancer have not been replaced and the survival rates have not changed.
Abramovich, Dalhia Nurit +7 more
core +1 more source
FEBS Letters, EarlyView.Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek +15 more
wiley +1 more source