Results 81 to 90 of about 927,276 (294)
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Angiogenesis in Chronic Obstructive Pulmonary Disease [PDF]
, 2012 Angiogenesis is a crucial component of lung pathophysiology, not only in cancer but also in other disorders, such as chronic obstructive pulmonary disease (COPD).
Gaetano Santulli, Alessandro Matarese
core
Quantitative assessment of angiogenesis in murine antigen-induced arthritis by intravital fluorescence microscopy [PDF]
, 2003 Inhibition of angiogenesis might be a therapeutic approach to prevent joint destruction caused by the overgrowing synovial tissue during chronic joint inflammation.
Schmitt-Sody, M. +7 more
core +1 more source
Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang +4 more
wiley +1 more source
MicroRNA-145 Regulates Pathological Retinal Angiogenesis by Suppression of TMOD3
Molecular Therapy: Nucleic Acids, 2019 Pathological angiogenesis is a hallmark of various vascular diseases, including vascular eye disorders. Dysregulation of microRNAs (miRNAs), a group of small regulatory RNAs, has been implicated in the regulation of ocular neovascularization.
Chi-Hsiu Liu +4 more
doaj +1 more source
EGFL7 meets miRNA-126 : an angiogenesis alliance [PDF]
, 2010 Blood vessels form de novo through the tightly regulated programs of vasculogenesis and angiogenesis. Both processes are distinct but one of the steps they share is the formation of a central lumen, when groups of cells organized as vascular cords ...
Plate, Karl +5 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand +5 more
wiley +1 more source
Angiogenesis inhibitors in cancer therapeutics [PDF]
, 2017 In the era molecular pharmacology, development of angiogenesis inhibitors is certainly a master discovery .There are specific angiogenesis inhibitors are being used in cancer and various endogenous anti-angiogenesis molecules are discovered .This review ...
Krishnan, V., Sadasivan, Usha
core
Highly tunable delivery of matrix-bound growth factors for therapeutic angiogenesis [PDF]
, 2014 Therapeutic angiogenesis is a promising strategy to treat pathologies characterized by insufficient blood supply to tissue, such as coronary and peripheral artery diseases, but also to promote the engraftment and survival of tissue-engineered constructs ...
Sacchi, Veronica
core +1 more source
Advanced Functional Materials, EarlyView.A swelling‐programmed micropatterned hydrogel guides adherent cells through a controlled transition from cell–matrix anchoring to cadherin‐mediated cell–cell compaction, enabling rapid assembly of high‐viability spheroids with defined size and morphology.
Han Gyeol Nam +8 more
wiley +1 more source