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Dependence on mitochondrial respiration of malignant T cells reveals a new therapeutic target for angioimmunoblastic T-cell lymphoma. [PDF]

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Angioimmunoblastic T-Cell Lymphoma

Hematology/Oncology Clinics of North America, 2017
Angioimmunoblastic T-cell lymphoma is a follicular T-helper-derived neoplasm displaying a peculiar morphologic appearance and biological complexity. New mutations have been described that contribute to elucidating the underlying pathogenetic events. The disease behaves aggressively and typically affects elderly patients.
BROCCOLI, ALESSANDRO   +1 more
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Angioimmunoblastic T-cell lymphoma

Critical Reviews in Oncology/Hematology, 2008
Angioimmunoblastic T-cell lymphoma (AITL) is a rare and aggressive neoplasm clinically characterized by sudden onset of constitutional symptoms, lymphadenopathy, hepatosplenomegaly, frequent autoimmune phenomena, particularly hemolytic anemia and thrombocytopenia, and polyclonal hypergammaglobulinemia.
IANNITTO, EMILIO   +4 more
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Angioimmunoblastic T-Cell Lymphoma

2018
Angioimmunoblastic T-cell lymphoma (AITL) is one of the most common types of T-cell lymphoma, representing about 15-20% of cases of peripheral T-cell lymphoma (PTCL). It is characterized by a unique clinical presentation and distinct pathologic and molecular features.
Mariko, Yabe   +3 more
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