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Angioimmunoblastic T-Cell Lymphoma
Hematology/Oncology Clinics of North America, 2017Angioimmunoblastic T-cell lymphoma is a follicular T-helper-derived neoplasm displaying a peculiar morphologic appearance and biological complexity. New mutations have been described that contribute to elucidating the underlying pathogenetic events. The disease behaves aggressively and typically affects elderly patients.
BROCCOLI, ALESSANDRO+1 more
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Angioimmunoblastic T‐cell lymphoma
British Journal of Haematology, 2003Angioimmunoblastic T-cell lymphoma (AITL) is one of the most common types of T-cell lymphoma, representing about 15–20% of cases of peripheral T-cell lymphoma (PTCL). It is characterized by a unique clinical presentation and distinct pathologic and molecular features.
Chara Kyriakou+2 more
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Angioimmunoblastic T-cell lymphoma
Critical Reviews in Oncology/Hematology, 2008Angioimmunoblastic T-cell lymphoma (AITL) is a rare and aggressive neoplasm clinically characterized by sudden onset of constitutional symptoms, lymphadenopathy, hepatosplenomegaly, frequent autoimmune phenomena, particularly hemolytic anemia and thrombocytopenia, and polyclonal hypergammaglobulinemia.
IANNITTO, EMILIO+4 more
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Angioimmunoblastic T-Cell Lymphoma
2018Angioimmunoblastic T-cell lymphoma (AITL) is one of the most common types of T-cell lymphoma, representing about 15-20% of cases of peripheral T-cell lymphoma (PTCL). It is characterized by a unique clinical presentation and distinct pathologic and molecular features.
Alison J. Moskowitz+3 more
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Angioimmunoblastic T-Cell Lymphoma Management
Seminars in Hematology, 2014Angioimmunoblastic T-cell lymphoma (AITL) is a frequent subtype of peripheral T-cell lymphoma (PTCL) that is clinically characterized by generalized lymphadenopathy, extranodal involvement, advanced stage at presentation, hypergammaglobulinemia, and significant immune dysregulation resulting in infections as the most common cause of death.
Julie M. Vose+2 more
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Angioimmunoblastic T-Cell Lymphoma
2013Angioimmunoblastic T-cell lymphoma (AITL) is a peripheral T-cell lymphoma that is associated with systemic manifestations and involves lymph nodes. The neoplasm is morphologically characterized by a polymorphous infiltrate associated with prominent high endothelial venules and follicular dendritic cell proliferation.
L. Jeffrey Medeiros+2 more
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Angioimmunoblastic T-Cell Lymphoma
Nihon rinsho. Japanese journal of clinical medicine, 2014Angioimmunoblastic T-cell lymphoma (AITL) is a subtype of nodal peripheral T-cell lymphoma associated with aggressive clinical course that affects mostly the elderly. Clinical features at diagnosis are characterized by polyclonal hypergammaglobulinemia, B-symptoms, and advanced stage.
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Angioimmunoblastic T-cell Lymphoma
Advances in Anatomic Pathology, 2002Angioimmunoblastic T-cell lymphoma (AIL-TCL) is a rare subtype of lymphoma, making up only 1% to 2% of nonHodgkin's lymphomas; however, it accounts for a major subset of peripheral T-cell lymphomas. Angioimmunoblastic T-cell lymphoma has clinical and pathologic features that set it apart from other B- and T-cell lymphomas.
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Angioimmunoblastic T-cell lymphoma mice model
Leukemia Research, 2013We established an angioimmunoblastic T-cell lymphoma (AITL) mouse model using NOD/Shi-scid, IL-2Rγ(null) mice as recipients. The immunohistological findings of the AITL mice were almost identical to those of patients with AITL. In addition, substantial amounts of human immunoglobulin G/A/M were detected in the sera of the AITL mice.
Hiroshi Inagaki+14 more
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