Results 21 to 30 of about 275,373 (195)

The Two Faces of Angiopoietin-Like Protein 2 in Cancer. [PDF]

open access: yesCancer Sci
ABSTRACTThe tumor microenvironment is composed of tumor cells and various stromal cell types, such as immune cells, fibroblasts, and vascular cells. Signaling interactions between tumor and stromal cells orchestrate the tumor microenvironment's contribution to tumor progression.
Horiguchi H, Kadomatsu T, Oike Y.
europepmc   +3 more sources

Angiopoietin‐like protein 4 and clinical outcomes in ischemic stroke patients

open access: yesAnnals of Clinical and Translational Neurology, 2021
Aims Angiopoietin‐like protein 4 (ANGPTL‐4) had been reported to be associated with the risk of ischemic stroke, but its prognostic value remained unclear.
Xiaowei Zheng   +13 more
doaj   +1 more source

A molecular clock regulates angiopoietin-like protein 2 expression. [PDF]

open access: yesPLoS ONE, 2013
Various physiological and behavioral processes exhibit circadian rhythmicity. These rhythms are usually maintained by negative feedback loops of core clock genes, namely, CLOCK, BMAL, PER, and CRY.
Tsuyoshi Kadomatsu   +11 more
doaj   +1 more source

Angiopoietin-like protein 2 inhibits thrombus formation. [PDF]

open access: yesMol Cell Biochem
Abstract Acute myocardial infarction is mainly caused by a lack of blood flood in the coronary artery. Angiopoietin-like protein 2 (ANGPTL2) induces platelet activation and thrombus formation in vitro through binding with immunoglobulin-like receptor B, an immunoglobulin superfamily receptor.
Zhang T   +11 more
europepmc   +3 more sources

Angiopoietin-like protein 4 regulates breast muscle lipid metabolism in broilers

open access: yesPoultry Science, 2021
: The objective of this study was to determine the effects of angiopoietin-like protein 4 (ANGPTL4) on breast muscle lipid metabolism in broilers. In experiment 1, 36 thirty-five-day-old male Arbor Acres broilers were randomly allocated into 6 treatment ...
Xu Zhao   +5 more
doaj   +1 more source

Angiopoietin-Like Protein 4 and Insulin-Like Growth Factor-1 Expression in Invasive Breast Carcinoma in Young Women

open access: yes, 2022
Biomarker identification is imperative for invasive breast carcinoma, which is more aggressive and associated with higher mortality and worse prognosis in younger patients (<45 years) than in older patients (>50 years).
Lam, AK   +9 more
core   +1 more source

The Prognostic Value of ANGPTL-4 in Acute Coronary Syndrome: A Prospective Cohort Study [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2018
Introduction: Coronary Artery Disease (CAD) is one of the leading causes of mortality and morbidity worldwide and Acute Coronary Syndrome (ACS) is one of the predominant causes of Cardiovascular Deaths (CVD).
Luxitaa Goenka   +4 more
doaj   +1 more source

Atypical angiopoietin-like protein that regulates ANGPTL3 [PDF]

open access: yesProceedings of the National Academy of Sciences, 2012
Angiopoietin-like proteins (ANGPTLs) play major roles in the trafficking and metabolism of lipids. Inactivation of ANGPTL3 , a gene located in an intron of DOCK7 , results in very low levels of LDL-cholesterol (C), HDL-C and triglyceride (TAG). We identified another ANGPTL family member,
Fabiana, Quagliarini   +9 more
openaire   +2 more sources

Angiopoietin-Like Proteins in Angiogenesis, Inflammation and Cancer [PDF]

open access: yesInternational Journal of Molecular Sciences, 2018
Altered expression of secreted factors by tumor cells or cells of the tumor microenvironment is a key event in cancer development and progression. In the last decade, emerging evidences supported the autocrine and paracrine activity of the members of the Angiopoietin-like (ANGPTL) protein family in angiogenesis, inflammation and in the regulation of ...
Carbone, Carmine   +7 more
openaire   +2 more sources

ApoA5 lowers triglyceride levels via suppression of ANGPTL3/8-mediated LPL inhibition

open access: yesJournal of Lipid Research, 2021
: Triglyceride (TG) molecules represent the major storage form of fatty acids, and TG metabolism is essential to human health. However, the mechanistic details surrounding TG metabolism are complex and incompletely elucidated.
Yan Q. Chen   +6 more
doaj   +1 more source

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