Results 131 to 140 of about 195,398 (256)

The Effects of Angiotensin Receptor Neprilysin Inhibitor on Endoplasmic Reticulum Stress in Doxorubicin‐Mediated Cardiomyopathy‐Associated Heart Failure Model in Rats

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT One of the most serious complications associated with the use of the chemotherapeutic agent doxorubicin (DOX) is cardiomyopathy. Although cardioprotective drugs such as angiotensin receptor‐neprilysin inhibitors (ARNI) are used to prevent cardiomyopathy in DOX patients, no studies have reported the relationship between ARNI and endoplasmic ...
Mert Unvan   +3 more
wiley   +1 more source

Single‐Cell Profiling Identifies CLEC5A+ Macrophages as Key Drivers of Thoracic Aortic Aneurysm Via CCL5‐Mediated M1 Polarization

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Thoracic aortic aneurysm (TAA) is a life‐threatening cardiovascular disease with limited therapeutic options. Through single‐cell RNA sequencing of aortic tissues from healthy individuals and TAA patients (105,541 cells), we identified CLEC5A+macrophages as the predominant pathogenic cell population exhibiting the highest M1 polarization score. Machine
Xiangyu Li   +3 more
wiley   +1 more source

Prenatal exposure to antihypertensive medication: A systematic review of neurodevelopmental and educational outcomes

open access: yesJCPP Advances, EarlyView.
This systematic review investigated the association of prenatal exposure to antihypertensive medication with longer‐term poor neurodevelopmental outcomes by evaluating the findings from existing literature. We undertook a systematic review of previous studies looking specifically at neurodevelopmental outcomes in children.
Shrifah Alkhalaf   +5 more
wiley   +1 more source

Abdominal pain in pediatric immunoglobulin A vasculitis: Risk factors and severity predictors in a multicenter cohort

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives To identify risk factors for abdominal pain and predictors of complicated abdominal pain in pediatric immunoglobulin A vasculitis (IgAV). Methods Retrospective multicenter study including children and adolescents (≤18 years) fulfilling the European League Against Rheumatism/Pediatric Rheumatology International Trials Organization ...
Francisco Hugo Rodrigues Gomes   +14 more
wiley   +1 more source

Expression of angiotensin-converting enzyme 2, transmembrane serine protease 2, and sirtuin 1 proteins in lungs of different age groups. [PDF]

open access: yesJ Bras Pneumol
Lamounier ACA   +6 more
europepmc   +1 more source

Biological activities and bioactive constituents of Flammulina velutipes: An updated systematic review

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract Flammulina velutipes (enokitake) is an edible mushroom recognized for both its nutritional and medicinal properties. It exhibits a broad spectrum of biological activities, including antioxidant, anti‐inflammatory, antitumor, immunomodulatory, and gut microbiota‐regulating effects.
Rıdvan Özgen   +2 more
wiley   +1 more source

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