The Adaptation of Complexity in the Evolution of Macromolecules [PDF]
Enzymes are on the front lines of evolution. All living organisms rely on highly efficient, specific enzymes for growth, sustenance, and reproduction; and many diseases are a consequence of a mutation on an enzyme that affects its catalytic function. It follows that the function of an enzyme affects the fitness of an organism, but just as rightfully ...
arxiv
An Intramolecularly Quenched Fluorescent Tripeptide as a Fluorogenic Substrate of Angiotensin‐I‐Converting Enzyme and of Bacterial Dipeptidyl Carboxypeptidase [PDF]
Amoes CARMEL, Arieh Yaron
openalex +1 more source
Angiotensin-converting enzyme 2 inhibits lung injury induced by respiratory syncytial virus
Respiratory syncytial virus (RSV) infection is a major cause of severe lower respiratory illness in infants and young children, but the underlying mechanisms responsible for viral pathogenesis have not been fully elucidated. To date, no drugs or vaccines
Hongjing Gu+17 more
semanticscholar +1 more source
Aims To develop an evidence‐ and consensus‐based patient prioritization tool for use by UK mental health inpatient pharmacy teams. Methods A modified‐Delphi technique was used to obtain experts' agreement on the content, design and practical use of the patient prioritization tool.
Fatima Q. Alshaikhmubarak+3 more
wiley +1 more source
The Effect of Eight-Week Aerobic Training on Serum Angiotensin Converting Enzyme and Lipid Profile in Inactive Overweight Women [PDF]
Background & Objective: At present, the prevalence of hypertension is growing and one of the contributing factors in the occurrence and development of hypertension and atherosclerosis is impaired renin–angiotensin system which in this system endothelium ...
nahid Bijeh+4 more
doaj
A novel method for quantifying enzyme immobilization in porous carriers using simple NMR relaxometry [PDF]
Enzyme immobilization plays a crucial role in enhancing the stability and recyclability of enzymes for industrial applications. However, traditional methods for quantifying enzyme loading within porous carriers are limited by time-consuming workflows, cumulative errors, and the inability to probe enzymes adsorbed inside the pores.
arxiv
Diagnostic value of serum angiotensin converting enzyme activity in lung diseases. [PDF]
Ashutosh Kumar, John Keighley
openalex +1 more source
Aims In this study, we examined the effects of assigning partial credit to selected answer choices on student performance and perceptions in a pharmacology course using Type A multiple‐choice questions (MCQs). Methods Partial credit scoring was incorporated into quizzes and exams in a 10‐week pharmacology course for postbaccalaureate premedical ...
Stephen D. Schneid+2 more
wiley +1 more source
Pharmacotherapy and analysis of gaseous mediators in hypertensive patients
OBJECTIVE To evaluate the effect of using antihypertensive classes of drugs of the calcium channel antagonists and inhibitors of angiotensin-converting enzyme in plasma concentrations of hydrogen sulfide and nitric oxide in patients with hypertension ...
Letícia Palota Eid+4 more
doaj +1 more source
The enzyme cost of given metabolic flux distributions, as a function of logarithmic metabolite levels, is convex [PDF]
Enzyme costs play a major role in the choice of metabolic routes, both in evolution and bioengineering. Given desired fluxes, necessary enzyme levels can be estimated based on known rate laws and on a principle of minimal enzyme cost. With logarithmic metabolite levels as free variables, enzyme cost functions and constraints in optimality and sampling ...
arxiv