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Mild hypothermia alleviates post-resuscitation cerebral injury in rats via modulating the balance of the renin–angiotensin system [PDF]
Resuscitation PlusCardiac arrest and cardiopulmonary resuscitation represent a major cause of mortality. Cerebral ischemia–reperfusion injury following Cardiac arrest and cardiopulmonary resuscitation leads to severe neurological deficits and significantly worsens patient
Yongjing He +8 more
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Physiopathology of the Brain Renin-Angiotensin System [PDF]
LifeThe renin-angiotensin system (RAS) has evolved from being considered solely a peripheral endocrine system for cardiovascular control to being recognized as a complex molecular network with important functions in the central nervous system (CNS) and ...
Cristina Cueto-Ureña +3 more
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Renin-Angiotensin System: A Review of Historical Perspectives
Galician Medical Journal, 2023 The article is a review of publications concerning historical perspectives of the renin-angiotensin system. The discovery of its components is presented in chronological order, beginning with the initial identification of renin and proceeding to the ...
Olga Kovalyova +2 more
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Renin Angiotensin System and Covid-19 Infection [PDF]
Advanced Pharmaceutical Bulletin, 2022 Purpose The new coronavirus, called SARS-CoV-2, is responsible for the recent global pandemic COVID-19. The status of the global pandemic COVID-19 is currently underway, and the virus has caused about 1.11 million deaths.
Francesco Ferrara, Antonio Vitiello
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Frontiers in Nutrition, 2021 Vitamin K2 (VK2), found to act to treat hypertension, has been widely used in the food and pharmaceutical industries nowadays. However, the potential targets and molecular mechanisms of VK2 for salt-sensitive hypertension have not been fully investigated.
Tian-hao Liu +7 more
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Hepcidin is potential regulator for renin activity
PLoS ONE, 2022 An association between genetic variants in the genes HFE, HJV, BMP4 and arterial hypertension has been shown earlier. Proteins encoded by these genes participate in the signalling routes leading eventually to the production of the peptide hormone ...
Jaakko Piesanen +7 more
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Journal of Pharmacological Sciences, 2010 Since renin inhibition interferes with the first and rate-limiting steps in the renin–angiotensin system, the renin step is a very attractive target for lowering blood pressure and minimizing target-organ damage.
Atsuhiro Ichihara +6 more
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BMC Nephrology, 2012 Background Dual renin-angiotensin system blockade with angiotensin-converting enzyme inhibitors and angiotensin receptor blockers has been advocated to minimize proteinuria. However, recent trials have questioned the renal safety of this approach.
Fernandez-Fernandez Beatriz +5 more
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The renin–angiotensin system: a possible new target for depression
BMC Medicine, 2017 Depression remains a debilitating condition with an uncertain aetiology. Recently, attention has been given to the renin–angiotensin system. In the central nervous system, angiotensin II may be important in multiple pathways related to neurodevelopment ...
João Vian +9 more
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Cardio and neuro protection by renin angiotensin aldosterone system-focus inhibition angiotensin converting enzyme: A systematic review [PDF]
BIO Web of ConferencesOne of the incidences of cardiovascular disease is stroke, which is a disease that occurs due to impaired brain function caused by damage to cerebral blood circulation.
Capritasari Rafiastiana +2 more
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