Results 1 to 10 of about 636,232 (298)

Decoding Angiotensin Receptors: TOMAHAQ‐Based Detection and Quantification of Angiotensin Type‐1 and Type‐2 Receptors

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background The renin‐angiotensin system plays a crucial role in human physiology, and its main hormone, angiotensin, activates 2 G‐protein–coupled receptors, the angiotensin type‐1 and type‐2 receptors, in almost every organ.
Caglar Cosarderelioglu, Simion Kreimer, Alma I. Plaza‐Rodriguez, Pablo A. Iglesias, C. Conover Talbot, Helmy M. Siragy, Robert M. Carey, Ceereena Ubaida‐Mohien, Brian O'Rourke, Luigi Ferrucci, David A. Bennett, Jeremy Walston, Peter Abadir   +12 more
doaj   +1 more source

Counter-regulatory renin–angiotensin system in cardiovascular disease

Nature Reviews Cardiology, 2019
The renin–angiotensin system is an important component of the cardiovascular system. Mounting evidence suggests that the metabolic products of angiotensin I and II — initially thought to be biologically inactive — have key roles in cardiovascular ...
Maria Paz Ocaranza, J. A. Riquelme, L. García, J. Jalil, M. Chiong, R. Santos, S. Lavandero   +6 more
semanticscholar   +1 more source

THE PATHOPHYSIOLOGY RELATIONSHIP OF HYPERTENSION AND RENAL HYPERTENSION

Jurnal Ilmiah Kedokteran Wijaya Kusuma, 2018
Introduction : Hypertension is a disease with an incidence rate is still high around the world, most of the causes of hypertension is unknown (essential hypertension / primary hypertension), a small portion of hypertension caused by diseases acquired ...
Akmarawita Kadir
doaj  

Angiotensin System Autoantibodies Correlate With Routine Prognostic Indicators for COVID-19 Severity

Frontiers in Medicine, 2022
ObjectiveWe previously showed that angiotensin type-1 receptor and ACE2 autoantibodies (AT1-AA, ACE2-AA) are associated with COVID-19 severity. Our aim is to find correlations of these autoantibodies with routine biochemical parameters that allow an ...
Carmen M. Labandeira, Carmen M. Labandeira, Maria A. Pedrosa, Juan A. Suarez-Quintanilla, María Cortes-Ayaso, José Luis Labandeira-García, José Luis Labandeira-García, Ana I. Rodríguez-Pérez, Ana I. Rodríguez-Pérez   +8 more
doaj   +1 more source

COVID‐19 and heart failure: from infection to inflammation and angiotensin II stimulation. Searching for evidence from a new disease

European Journal of Heart Failure, 2020
Patients with cardiovascular disease and, namely, heart failure are more susceptible to coronavirus disease 2019 (COVID‐19) and have a more severe clinical course once infected.
D. Tomasoni, L. Italia, M. Adamo, R. Inciardi, C. Lombardi, S. Solomon, M. Metra   +6 more
semanticscholar   +1 more source

CD4+ Regulatory T Lymphocytes Prevent Impaired Cerebral Blood Flow in Angiotensin II‐Induced Hypertension

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Immune cells are key regulators of the vascular inflammatory response characteristic of hypertension. In hypertensive rodents, regulatory T lymphocytes (Treg, CD4+CD25+) prevented vascular injury, cardiac damage, and endothelial dysfunction of
M. Florencia Iulita, Sonia Duchemin, Diane Vallerand, Tlili Barhoumi, Fernando Alvarez, Roman Istomine, Cyril Laurent, Jessica Youwakim, Pierre Paradis, Nathalie Arbour, Ciriaco A. Piccirillo, Ernesto L. Schiffrin, Hélène Girouard   +12 more
doaj   +1 more source

Renin and Survival in Patients Given Angiotensin II for Catecholamine-Resistant Vasodilatory Shock. A Clinical Trial

American Journal of Respiratory and Critical Care Medicine, 2020
Rationale: Exogenous angiotensin II increases mean arterial pressure in patients with catecholamine-resistant vasodilatory shock (CRVS). We hypothesized that renin concentrations may identify patients most likely to benefit from such therapy. Objectives:
R. Bellomo, L. Forni, Laurence W. Busse, M. McCurdy, K. Ham, D. Boldt, Johanna Hästbacka, A. Khanna, T. Albertson, J. Tumlin, Kristine Storey, D. Handisides, G. Tidmarsh, L. Chawla, M. Ostermann   +14 more
semanticscholar   +1 more source

A pilot clinical trial of recombinant human angiotensin-converting enzyme 2 in acute respiratory distress syndrome

Critical Care, 2017
BackgroundRenin-angiotensin system (RAS) signaling and angiotensin-converting enzyme 2 (ACE2) have been implicated in the pathogenesis of acute respiratory distress syndrome (ARDS).
Akram Khan, Cody Benthin, B. Zeno, T. Albertson, J. Boyd, J. Christie, R. Hall, G. Poirier, J. Ronco, M. Tidswell, K. Hardes, W. Powley, T. Wright, S. Siederer, D. Fairman, D. Lipson, Andrew I. Bayliffe, A. Lazaar   +17 more
semanticscholar   +1 more source

Interdialytic blood pressure is independent of weight gain and correlated with serum angiotensin II levels in adults

Physiological Reports
Chronic volume overload is a major risk factor of hypertension and mortality in chronic dialysis patients. However, the mechanisms responsible for hypertension are unclear. We studied 32 patients (age 23–68 years, 19 females) in chronic hemodiafiltration
Adolfo Diaz, Brenda Delgado, Eduardo R. Argaiz, Olynka Vega, Ricardo Correa‐Rotter, Bernardo Rodriguez‐Iturbe   +5 more
doaj   +1 more source

Effects of HIIT and MICT on cardiovascular function in essential hypertension: roles of inflammation, oxidative stress, and RAS axis

Frontiers in Cardiovascular Medicine
ObjectiveTo compare the effects of High Intensity Interval Training (HIIT) and Moderate Intensity Continuous Training (MICT) on blood pressure homeostasis, cardiovascular structure, and function, and to explore the underlying neuro-humoral regulatory ...
Zhiwei Yan, Xiao Liu, Xiao Liu, Xiaofan Gao, Yaodong Guo, Hancheng Wu, Yu Gong, Yan Gao, Yuan Wang   +8 more
doaj   +1 more source