Results 21 to 30 of about 313,972 (268)

Osmotic Adaptation by Na⁺-Dependent Transporters and ACE2: Correlation with Hemostatic Crisis in COVID-19

Biomedicines, 2020
COVID-19 symptoms, including hypokalemia, hypoalbuminemia, ageusia, neurological dysfunctions, D-dimer production, and multi-organ microthrombosis reach beyond effects attributed to impaired angiotensin-converting enzyme 2 (ACE2) signaling and elevated ...
Danah Muhanna, Shanvanth R. Arnipalli, Shashi B. Kumar, Ouliana Ziouzenkova   +3 more
doaj   +1 more source

Angiotensin-Converting Enzyme 2 (ACE2) in the Context of Respiratory Diseases and Its Importance in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection

Pharmaceuticals, 2021
Angiotensin-Converting Enzyme 2 (ACE2) is an 805 amino acid protein encoded by the ACE2 gene expressed in various human cells, especially in those located in the epithelia. The primary function of ACE2 is to produce angiotensin (1–7) from angiotensin II (
Enrique Ambrocio-Ortiz, Gloria Pérez-Rubio, Alma D. Del Ángel-Pablo, Ivette Buendía-Roldán, Leslie Chávez-Galán, Rafael de Jesús Hernández-Zenteno, Alejandra Ramírez-Venegas, Jorge Rojas-Serrano, Mayra Mejía, Rogelio Pérez-Padilla, Cristóbal Guadarrama-Pérez, Ramcés Falfán-Valencia   +11 more
doaj   +1 more source

Perinatal changes in estradiol and Ang II concentrations in pregnant women with pulmonary arterial hypertension and their correlation

Hypertension in Pregnancy, 2019
Objective: This study aimed to analyze the perinatal changes of plasma estradiol (E2) and angiotensin II (Ang II) in pregnant women with pulmonary arterial hypertension before and after cesarean section. Methods: Depending on pulmonary arterial pressure,
Yanshuang Wang, Hao Che, Kai Kang, Guosheng Zhao, Xiaoguang Li, Xiangming Che, Mingjun Xu, Liyun Zhao   +7 more
doaj   +1 more source

The diagnostic value of angiotensin, g-GT, blood lactate, and renal resistance index combined detection in acute kidney injury after neonatal asphyxia [PDF]

Journal of Medical Biochemistry
Background: To investigate the diagnostic value of angiotensin (Ang), gamma-glutamyltransferase (g-GT), blood lactic acid and renal resistive index (RRI) for acute kidney injury (AKI) after neonatal asphyxia.
Shi Xiaoqing, Dai Liying, Wang Ying, Deng Fang   +3 more
doaj   +1 more source

Angiotensin II-Induced Cardiovascular Fibrosis Is Attenuated by NO-Sensitive Guanylyl Cyclase1

Cells, 2020
In the NO/cGMP signaling cascade, relevant in the cardiovascular system, two NO-sensitive guanylyl cyclase (NO-GC) isoforms are responsible for NO-dependent cGMP generation.
Kathrin Broekmans, Jan Giesen, Lukas Menges, Doris Koesling, Michael Russwurm   +4 more
doaj   +1 more source

Aldosterone-Regulating Receptors and Aldosterone-Driver Somatic Mutations

Frontiers in Endocrinology, 2021
BackgroundSomatic gene mutations that facilitate inappropriate intracellular calcium entrance have been identified in most aldosterone-producing adenomas (APAs).
Jung Soo Lim, Jung Soo Lim, Samuel W. Plaska, Juilee Rege, William E. Rainey, William E. Rainey, Adina F. Turcu   +6 more
doaj   +1 more source

Treatment of hypertension with angiotensin‐converting enzyme inhibitors or angiotensin receptor blockers and resting metabolic rate: A cross‐sectional study

The Journal of Clinical Hypertension, 2021
Hypertension in obese and overweight patients is associated with an elevated resting metabolic rate (RMR). The aim of this study was to determine whether RMR is reduced in hypertensive patients treated with angiotensin‐converting enzyme inhibitors (ACEI)
Pablo B. Pedrianes‐Martin, Marcos Martin‐Rincon, David Morales‐Alamo, Ismael Perez‐Suarez, Mario Perez‐Valera, Victor Galvan‐Alvarez, David Curtelin, Pedro dePablos‐Velasco, Jose A.L. Calbet   +8 more
doaj   +1 more source

Mineralocorticoid axis activity and cardiac remodeling in patients with ACTH-dependent Cushing’s syndrome

Endocrine Connections
Background: Arterial hypertension and left ventricular hypertrophy and remodeling are independent cardiovascular risk factors in patients with Cushing’s syndrome. Changes in the renin–angiotensin system and in the mineralocorticoid axis activity could be
Peter Wolf, Simon Travers, Oliver Domenig, Stephanie Baron, Anne Blanchard, Khaoula Bouazizi, Nadjia Kachenoura, Sylvie Salenave, Marko Poglitsch, Alban Redheuil, Severine Trabado, Jacques Young, Philippe Chanson, Peter Kamenický   +13 more
doaj   +1 more source

ACE2, Much More Than Just a Receptor for SARS-COV-2

Frontiers in Cellular and Infection Microbiology, 2020
The rapidly evolving pandemic of severe acute respiratory syndrome coronavirus (SARS-CoV-2) infection worldwide cost many lives. The angiotensin converting enzyme-2 (ACE-2) has been identified as the receptor for the SARS-CoV-2 viral entry.
Lobelia Samavati, Lobelia Samavati, Bruce D. Uhal   +2 more
doaj   +1 more source

Primary aldosteronism and obstructive sleep apnea: What do we know thus far?

Frontiers in Endocrinology, 2022
Both primary aldosteronism and obstructive sleep apnea are well-known causes of hypertension and contribute to increased cardiovascular morbidity and mortality independently.
Huai Heng Loh, Huai Heng Loh, Norlela Sukor   +2 more
doaj   +1 more source