Results 241 to 250 of about 212,078 (304)

Long non-coding RNA enhances SARS-CoV-2-mediated apoptosis through epigenetic repression of angiotensin-converting enzyme 2. [PDF]

J Biol Chem
Liao W, Zhang T, Cao J, Wang S, Zhang Y.
europepmc   +1 more source

OSA Initiates Histone Lactylation That Drives PDE4B/FUS/AGT Axis to Pulmonary Hypertension

Cell Proliferation, EarlyView.
This study illustrates how chronic intermittent hypoxia (CIH) in obstructive sleep apnea (OSA) leads to hypertension via increased oxidative stress and mitochondrial dysfunction in pulmonary artery smooth muscle cells (PASMCs), causing glycolytic dysregulation. Lactate accumulation enhances histone lactylation, upregulating phosphodiesterase 4B (PDE4B),
Li Yang, Qing Ni, Yan He, Shijie Liu, Lulu Gan, Anni Dai, Yang Hu, Qian Liu, Xueling Yang, Jiqian Li, Yi Tao, Yunyu Li, Mingyue Xu   +12 more
wiley   +1 more source

A GWAS of angiotensin-converting enzyme inhibitor-induced angioedema in a South African population. [PDF]

J Allergy Clin Immunol Glob
Mugo JW, Day C, Choudhury A, Deetlefs M, Freercks R, Geraty S, Panieri A, Cotchobos C, Ribeiro M, Engelbrecht A, Micklesfield LK, Ramsay M, Pedretti S, Peter J.   +13 more
europepmc   +1 more source

Progression of albumin/creatinine ratio (ACR) and estimated glomerular filtration rate (eGFR) over 24 years in people with type 2 diabetes. Drivers, potential protectors and associated mortality

Diabetic Medicine, EarlyView.
Abstract Introduction The pathophysiology of chronic kidney disease (CKD) and type 2 diabetes (T2D) is multifactorial and associated with a plethora of underlying conditions and complications. Their link is reciprocal and understanding its nature, particularly over time, could improve the health of many.
Andreas Matheou, Orestis Zavlis, Steve White, Thomas McDonnell, Alexander Warner‐Levy, John Warner‐Levy, Loren Wilkins, Hellena Habte‐Asres, Abigail Lay, Liliana Shalamanova, Martin Whyte, Martin Gibson, Philip A. Kalra, Adrian Heald   +13 more
wiley   +1 more source

Letter to the Editor: "Reducing the Risk of Developing Diabetes: The Role of Angiotensin Receptor Blockers and Angiotensin Converting Enzyme Inhibitors in Patients With Hypertension Combined Prediabetes". [PDF]

J Clin Hypertens (Greenwich)
Ayesha S, Ishtiaq S, Ali MI, Huda NU.
europepmc   +1 more source

Work productivity, associated risk factors and costs on presenteeism and absenteeism in Chinese patients with young‐onset type‐2 diabetes in Hong Kong

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Those with young‐onset type‐2 diabetes (YOD), diagnosed before age of 40 years, experience heightened risk of complications. The economic burden extends beyond medical costs, impacting work productivity. Materials and Methods Chinese patients with YOD were recruited between June 2023 and April 2024 in the Precision Medicine to redefine ...
Juliana N. M. Lui, Kelly T. C. Wong, Eric S. H. Lau, Sunny C. S. Chan, Nga Sze Wong, Jenny Y. Z. Zhang, Kit Ming Wai, Chun Kwan O, Baoqi Fan, Hongjiang Wu, Ronald C. W. Ma, Alice P. S. Kong, Andrea O. Y. Luk, Elaine Y. K. Chow, Juliana C. N. Chan   +14 more
wiley   +1 more source

Angiotensin-Converting Enzyme Inhibitors Mitigate Development of Chronic Persistent Cardiac Dysfunction Following Fulminant Myocarditis: A Multicenter Retrospective Study in China. [PDF]

Int J Gen Med
Yang H, Qidamugai W, Wang L, Liu F, He Y, Xu Z, Zhang L, Li F, Wang H, Jiang J.   +9 more
europepmc   +1 more source

Use of sodium‐glucose cotransporter‐2 inhibitors among older adults with type 2 diabetes mellitus in British Columbia

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Clinical guidelines recommend sodium‐glucose cotransporter‐2 inhibitors (SGLT2is) for individuals with type 2 diabetes mellitus (T2DM) and established or high risk of cardiorenal disease. This study examined real‐world SGLT2i use patterns among older adults with T2DM in British Columbia, Canada.
Hanin Harbi, Gregory Carney, Colin Dormuth, Jacob Volmer Stidsen, Iliana Lega, Lisa M. McCarthy, Guillaume Grenet, Anshula Ambasta, Raha Eskandari, Anton Pottegård, Wade Thompson   +10 more
wiley   +1 more source

Investigation of Epstein-Barr virus coinfection and changes in the gene expression of angiotensin converting enzyme II in peripheral blood mononuclear cells in COVID-19 patients. [PDF]

Biochem Biophys Rep
Lajmiri H, Ahmadi N, Ebrahimi S, Nikoo HR, Farrokhnia M, Heidari E, Mousavi E.   +6 more
europepmc   +1 more source

Peritoneal Sarcoidosis

ANZ Journal of Surgery, EarlyView.
Luiz Eduardo Correia Miranda, André Bezerra de Sena, Raphael Brito Vieira   +2 more
wiley   +1 more source