Results 301 to 310 of about 470,839 (363)

Effects of angiotensin converting enzyme inhibition in adult polycystic kidney disease

, 1992
Michael L. Watson, A M Macnicol, Paul L. Allan, Alan F. Wright   +3 more
openalex   +1 more source

The utility of urine biomarkers in diuretic resistance prediction in heart failure hospitalization

ESC Heart Failure, EarlyView.
High urine pi‐GST concentration might be a marker for the development of loop diuretic resistance in patients with congestive heart failure hospitalization. Abstract Aims Loop diuretic resistance (LDR) in patients with heart failure hospitalization (HHF) is associated with worse clinical outcomes.
Tomasz Imiela, Piotr Poplawski, Beata Zaborska, Ewa Pilichowska‐Paszkiet, Anna M. Imiela, Tomasz Bednarczyk, Katarzyna Piszcz, Andrzej Budaj   +7 more
wiley   +1 more source

Development of a trispecific fusion protein based on angiotensin-converting enzyme 2, glycoprotein 130, and tumor necrosis factor receptor 2 as a promising therapeutic for COVID-19. [PDF]

Mol Biomed
Qiao Y, Han Y, Zhao L, Gao W, Hu H, Su C, Zheng A, Sun J, Tian M, Wu Y, Bai L, Lei Y, Wu J, Zhang W, Han P, Li X, Dong C, Wang H, Liu Z, Han P.   +19 more
europepmc   +1 more source

Cardioimmunologic response patterns after an acute heart failure event: Design and first results of AHF‐ImmunoCS

ESC Heart Failure, EarlyView.
Abstract Aims We have previously shown that patients who develop heart‐reactive antibodies (HRAs) de novo after a heart failure (HF) hospitalization are at increased risk of adverse outcomes, lending weight to the hypothesis that B cells may play a pivotal role in HF progression.
Niklas Beyersdorf, Boshra Afshar, Dora Pelin, Maximilian Bauser, Elisa Kaiser, Janna Lamers, Jannika Pätkau, Mairin Heil, Dennis Göpfert, Hanna Hepp, Wafaa Al Hassan, Thomas Kerkau, Fabian Kerwagen, Roland Jahns, Valerie Boivin‐Jahns, Stefan Frantz, Gustavo Ramos, Ulrich Hofmann, Stefan Störk, Caroline Morbach   +19 more
wiley   +1 more source

A promise to save 100,000 trauma patients.

, 2013
Horton, Richard, Krug, Etienne, Mersch, Jeannot, Piot, Peter, Roberts, Ian, Shakur, Haleema   +5 more
core   +1 more source

Albuminuria is associated with worse outcomes in non‐diabetics hospitalized with acute heart failure

ESC Heart Failure, EarlyView.
Abstract Aims Chronic kidney disease (CKD) increases the risk of morbidity and mortality in patients with heart failure (HF). Guidelines recommend assessing CKD using the urinary albumin‐to‐creatinine ratio (UACR), as albuminuria is strongly associated with the risk of incident HF and outcomes in chronic HF; however, its prognostic role in acute HF ...
Yoshimitsu Takaoka, Yu Horiuchi, Michael Strader, Patrick Murray, Nicholas Wettersten   +4 more
wiley   +1 more source

Autoantibodies targeting angiotensin-converting enzyme 2 are prevalent and not induced by SARS-CoV-2 infection. [PDF]

FASEB J
Galipeau Y, Castonguay N, McCluskie PS, Sonoda MT, Keeshan A, Collins E, Arnold C, Pelchat M, Burns K, Cooper C, Langlois MA.   +10 more
europepmc   +1 more source

Transcriptomic and proteomic profiling shows dysregulated immune and metabolic pathways in arrhythmogenic cardiomyopathy

ESC Heart Failure, EarlyView.
Abstract Aims Arrhythmogenic cardiomyopathy (ACM) is a hereditary heart disease characterized by fibrofatty myocardial replacement and a predisposition to malignant ventricular arrhythmias. The underlying pathomechanisms remain incompletely understood, and specific disease markers are sparse.
Deniz Akdis, Lukas Weidmann, Paolo Nanni, Anna Gaertner, Hendrik Milting, Peter Bode, Corinna Brunckhorst, Liang Chen, Felix C. Tanner, Frank Ruschitzka, Ardan M. Saguner, Firat Duru   +11 more
wiley   +1 more source

The transcriptional profile of iron deficiency in patients with heart failure: Heme‐sparing and reduced immune processes

European Journal of Heart Failure, EarlyView.
The analysis workflow, findings and potential clinical consequences of iron deficiency in heart failure (HF). From 881 patients with worsening HF, whole blood transcriptome was analysed using the Affymetrix Human Transcriptome Array (HTA) 2.0. Subjects were stratified according to their transferrin saturation (TSAT) levels as iron‐deficient (TSAT <20%)
Niels Grote Beverborg, Ridha I.S. Alnuwaysir, George Markousis‐Mavrogenis, Martijn F. Hoes, Haye H. van der Wal, Simon P.R. Romaine, Mintu Nath, Andrea Koekoemoer, John G.F. Cleland, Chim C. Lang, Stefan D. Anker, Kenneth Dickstein, Marco Metra, Leong L. Ng, Dirk J. van Veldhuisen, Adriaan A. Voors, Nilesh J. Samani, Peter van der Meer   +17 more
wiley   +1 more source