Soluble angiotensin-converting enzyme 2: a potential approach for coronavirus infection therapy?
Clinical science, 2020 A new coronavirus, referred to as SARS-CoV-2, is responsible for the recent outbreak of severe respiratory disease. This outbreak first detected in Wuhan, China in December 2019, has spread to other regions of China and to 25 other countries as of ...
D. Batlle +2 more
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A new angiotensin-converting enzyme inhibitor from Peperomia pellucida (L.) Kunth
Asian Pacific Journal of Tropical Biomedicine, 2019 Objective: To isolate, identify, and evaluate a new angiotensin-converting enzyme inhibitor from Peperomia pellucida (L.) Kunth herbs. Methods: A dried sample of Peperomia pellucida herb was successively macerated with n-hexane and ethyl acetate.
Islamudin Ahmad +7 more
doaj +1 more source
Journal of Veterinary Internal Medicine, 2020 Background An angiotensin‐converting enzyme (ACE) gene polymorphism occurs in dogs; however, functional importance is not well studied. Hypothesis We hypothesized that dogs with the polymorphism would show alternative renin‐angiotensin aldosterone system
Darcy Adin +7 more
doaj +1 more source
The effect of chronic peripheral nesfatin-1 application on blood pressure in normal and chronic restraint stressed rats: Related with circulating level of blood pressure regulators [PDF]
, 2015 Nesfatin is a peptide secreted by peripheral tissues, central and peripheral nervous system. It is involved in the regulation of homeostasis. Although the effects of nesfatin-1 on nutrition have been studied widely in the literature, the mechanisms of ...
Ayada, C. +3 more
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Angiotensin II and COVID-19. Secrets of interactions
Российский кардиологический журнал, 2020 The article describes current data on the relationship of renin-angiotensin system and related drugs with the risk of COVID-19 infection and its outcomes.
A. O. Konradi, A. O. Nedoshivin
doaj +1 more source
Accelerated search kinetics mediated by redox reactions of DNA repair enzymes [PDF]
Biophysical Journal, volume 96, pp 3949-3958, (2009), 2009 A Charge Transport (CT) mechanism has been proposed in several papers (e.g., Yavin, et al. PNAS, v102 3546 (2005)) to explain the localization of Base Excision Repair (BER) enzymes to lesions on DNA. The CT mechanism relies on redox reactions of iron-sulfur cofactors that modify the enzyme's binding affinity.
arxiv +1 more source
Journal of Medical Virology, 2020 This article reviews the correlation between angiotensin‐converting enzyme 2 (ACE2) and severe risk factors for coronavirus disease 2019 (COVID‐19) and the possible mechanisms. ACE2 is a crucial component of the renin‐angiotensin system (RAS).
Hao Cheng, Yan Wang, gui-qiang Wang
semanticscholar +1 more source
Association between peri‐operative angiotensin‐converting enzyme inhibitors and angiotensin‐2 receptor blockers and acute kidney injury in major elective non‐cardiac surgery:a multicentre, prospective cohort study [PDF]
, 2018 The peri-operative use of angiotensin-converting enzyme inhibitors or angiotensin-2 receptor blockers is thought to be associated with an increased risk of postoperative acute kidney injury.
core +3 more sources
ACE-I induced angioedema: a case report and review of literature [PDF]
, 2009 Although rare, angioedema has been documented to occur following the administration of angiotensin-Converting Enzyme Inhibitors. Angiotensin-converting enzyme inhibitors are the leading cause of drug induced angioedema.
Adebayo, Philip Babatunde +1 more
core +3 more sources
European Heart Journal, 2020 Aims The current pandemic coronavirus SARS-CoV-2 infects a wide age group but predominantly elderly individuals, especially men and those with cardiovascular disease. Recent reports suggest an association with use of renin–angiotensin–aldosterone system (
I. Sama +17 more
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