Results 31 to 40 of about 462,118 (388)

Circulating plasma concentrations of angiotensin-converting enzyme 2 in men and women with heart failure and effects of renin–angiotensin–aldosterone inhibitors

European Heart Journal, 2020
Aims The current pandemic coronavirus SARS-CoV-2 infects a wide age group but predominantly elderly individuals, especially men and those with cardiovascular disease. Recent reports suggest an association with use of renin–angiotensin–aldosterone system (
I. Sama, Alice Ravera, B. Santema, H. van Goor, J. T. ter Maaten, J. Cleland, M. Rienstra, A. Friedrich, N. Samani, L. Ng, K. Dickstein, C. Lang, G. Filippatos, S. Anker, P. Ponikowski, M. Metra, D. V. van Veldhuisen, A. Voors   +17 more
semanticscholar   +1 more source

Angiotensin receptor blockers and risk of dementia: cohort study in UK Clinical Practice Research Datalink. [PDF]

, 2014
AIMS: This was a cohort study to evaluate whether individuals exposed to angiotensin receptor blockers have a reduced risk of dementia compared with those exposed to angiotensin-converting enzyme inhibitors.
Bhaskaran, Krishnan, Douglas, Ian J, Evans, Stephen JW, Goh, Kah L, Minassian, Caroline, Smeeth, Liam   +5 more
core   +1 more source

Coronavirus Disease 2019 (COVID‐19) and Cardiovascular Disease: A Viewpoint on the Potential Influence of Angiotensin‐Converting Enzyme Inhibitors/Angiotensin Receptor Blockers on Onset and Severity of Severe Acute Respiratory Syndrome Coronavirus 2 Infection

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2020
recent study confirmed that respiratory syndrome uses severe acute respiratory syndrome coronavirus (SARS- CoV) angiotensin- converting enzyme 2 (ACE2) for ...
Junyi Guo, Zheng Huang, Li Lin, Jiagao Lv   +3 more
semanticscholar   +1 more source

Antecedent Administration of Angiotensin‐Converting Enzyme Inhibitors or Angiotensin II Receptor Antagonists and Survival After Hospitalization for COVID‐19 Syndrome

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) utilizes the angiotensin‐converting enzyme‐2 (ACE‐2) receptor to enter human cells.
Alberto Palazzuoli, Massimo Mancone, Gaetano M. De Ferrari, Giovanni Forleo, Gioel G. Secco, Gaetano M. Ruocco, Fabrizio D'Ascenzo, Silvia Monticone, Anita Paggi, Marco Vicenzi, Anna G. Palazzo, Maurizio Landolina, Erika Taravelli, Guido Tavazzi, Francesco Blasi, Fabio Infusino, Francesco Fedele, Francesco G. De Rosa, Michael Emmett, Jeffrey M. Schussler, Kristen M. Tecson, Peter A. McCullough   +21 more
doaj   +1 more source

Angiotensin-Converting Enzyme and Heart Failure

Frontiers in Bioscience-Landmark, 2023
Pharmacotherapy is the cornerstone treatment for patients with heart failure (HF) that uses drugs targeting the renin-angiotensin-aldosterone system (RAAS), including angiotensin-converting enzyme (ACE) inhibitors, angiotensin receptor blockers (ARBs ...
Sara Álvarez-Zaballos, Manuel Martínez-Sellés   +1 more
doaj   +1 more source

Enalaprilat and losartan decrease erythroid precursors frequency in cells from patients with polycythemia vera

Hematology, 2023
Objective: Polycythemia Vera (PV) is a myeloproliferative neoplasm characterized by the overproduction of red blood cells. First-line therapies are directed at lowering hematocrit levels. After the discovery of a mutation in the Janus kinase 2 (JAK2V617F)
Angela Bozza, Martina Bernardi, Daniela Catanzaro, Katia Chieregato, Anna Merlo, Giuseppe Astori   +5 more
doaj   +1 more source

Significant correlation of angiotensin converting enzyme and glycoprotein IIIa genes polymorphisms with unexplained recurrent pregnancy loss in north of Iran [PDF]

, 2016
Background: Spontaneous abortion is considered as the most complex problem during pregnancy. Thrombophilia is resumed as a cause of recurrent pregnancy loss (RPL). Glycoprotein IIIa (GPIIIa) gene is involved in thrombosis and abortion.
Farazmandfar, T., Fazelnia, S., Hashemi-Soteh, S.M.B.   +2 more
core   +1 more source

Hypothesis: angiotensin-converting enzyme inhibitors and angiotensin receptor blockers may increase the risk of severe COVID-19

Journal of Travel Medicine, 2020
Highlight Intravenous infusions of angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) in experimental animals increase the numbers of angiotensin-converting enzyme 2 (ACE2) receptors in the cardiopulmonary ...
J. Diaz
semanticscholar   +1 more source

Comparative effectiveness of enalapril, lisinopril, and ramipril in the treatment of patients with chronic heart failure: a propensity score-matched cohort study [PDF]

, 2017
Background: Angiotensin converting enzyme inhibitors (ACEIs) are recommended as first-line therapy in patients with heart failure with reduced ejection fraction (HFrEF). The comparative effectiveness of different ACEIs is not known. Methods and results:
Agewall, Stefan, Atar, Dan, Clark, Andrew L., Cleland, John G.F., Corletto, Anna, Frankenstein, Lutz, Fröhlich, Hanna, Goode, Kevin, Grundtvig, Morten, Henning, Felix, Hole, Torstein, Katus, Hugo A., Kazmi, Syed, Schellberg, Dieter, Täger, Tobias   +14 more
core   +1 more source

Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus

Nature, 2003
Spike (S) proteins of coronaviruses, including the coronavirus that causes severe acute respiratory syndrome (SARS), associate with cellular receptors to mediate infection of their target cells. Here we identify a metallopeptidase, angiotensin-converting
Wenhui Li, M. J. Moore, N. Vasilieva, J. Sui, S. Wong, M. Berne, M. Somasundaran, J. Sullivan, K. Luzuriaga, T. Greenough, H. Choe, M. Farzan   +11 more
semanticscholar   +1 more source