Results 391 to 400 of about 456,743 (411)

Angiotensin-converting enzyme inhibitors

2001
Publisher Summary Angiotensin-converting enzyme (ACE) inhibitors were first studied clinically in the 1970s. ACE inhibitors were discovered by taking advantage of previous basic research on the physiology of sodium, potassium, and water homeostasis and blood pressure regulation, in a reciprocal way ACE have also advanced research in this field, and ...
Arthur A. Patchett, Joël Ménard
openaire   +3 more sources

Assay of Tissue Angiotensin Converting Enzyme

Journal of Cardiovascular Pharmacology, 1989
The distinction between a circulating renin-angiotensin system and a tissue renin-angiotensin system led us to determine tissue angiotensin converting enzyme (ACE) activity. This study establishes the experimental conditions for a good reproducibility of the fluorimetric assay of ACE and describes the use of [3H]ramiprilat to characterize ACE ...
Jean-Louis Imbs, Jean-Jacques Helwig, Mariette Barthelmebs, C. Coquard, C. Welsch, Michèle Grima, E. M. Giesen   +6 more
openaire   +3 more sources

Angiotensin-Converting Enzyme Inhibitors

Medical Clinics of North America, 1987
In summary, ACE inhibitors are effective in reducing blood pressure as initial therapy in some hypertensive patients and in combination with diuretics and other agents in virtually all hypertensives. ACE inhibitors are uniquely advantageous because of their favorable hemodynamic effects, the lack of adverse metabolic effects, and their ability to ...
openaire   +3 more sources

2 Inhibitiors of Angiotensin-Converting Enzyme

1980
Publisher Summary This chapter focuses on the development, mechanism of action, and biological activity of two distinct classes of therapeutically useful inhibitors of angiotensin-converting enzyme: the snake venom peptides and a newly developed class of orally active inhibitors that were designed for specific binding to the active site of this ...
David W. Cushman, Miguel A. Ondetti
openaire   +3 more sources

Angiotensin-converting enzyme inhibition and prostaglandins

The American Journal of Cardiology, 1982
To determine whether prostaglandins contribute to the depressor response of angiotensin-converting enzyme inhibitors, plasma prostaglandin levels were measured by radioimmunoassay in normo- and hypertensive subjects on both sodium-restricted and sodium-loaded diets before and after captopril administration.
Stephen L. Swartz, Gordon H. Williams
openaire   +3 more sources

The Future of Angiotensin-Converting Enzyme Inhibitors

Journal of Cardiovascular Pharmacology, 1985
After a brief introduction summarizing their historical development and the classification of angiotensin-converting enzyme inhibitors by chemical structure, the considerations involved in developing new and improved drugs of this pharmacologic class are discussed.
openaire   +3 more sources

Enzymes in Sarcoidosis: Angiotensin-Converting-Enzyme (ACE)

Clinics in Laboratory Medicine, 1989
Measurement of serum angiotensin-converting-enzyme (SACE) is the most useful test for diagnosing and monitoring disease activity in sarcoidosis. Because elevated levels of SACE are not specific for sarcoidosis, other conditions in which SACE levels are also elevated are examined.
openaire   +3 more sources

The Leech Angiotensin‐Converting Enzyme

Annals of the New York Academy of Sciences, 1998
Michel Salzet, George B. Stefano, Virginie Laurent   +2 more
openaire   +3 more sources

Faculty Opinions recommendation of Angiotensin-Converting Enzyme 2: SARS-CoV-2 Receptor and Regulator of the Renin-Angiotensin System: Celebrating the 20th Anniversary of the Discovery of ACE2.

, 2020
T. Hussain
semanticscholar   +1 more source

Angiotensin‐Converting enzyme inhibitors

Medical Journal of Australia, 1994
openaire   +6 more sources