Results 241 to 250 of about 365,351 (311)

Paradoxical sex differences in a hamster model of angiotensin II-dependent hypertension and associated renal injury. [PDF]

Biol Sex Differ
Ji H, Nascimento LGD, Ahn J, Kwon DH, Williams G, Wu X, Speth RC, Hawks SA, Duggal NK, Saavedra JM, Sandberg K, de Souza AMA.   +11 more
europepmc   +1 more source

Mapping the Global Clinical Landscape of Pharmacological Therapies for Heart Failure With Preserved Ejection Fraction: An Analysis Based on ClinicalTrials.gov (2003–2025)

iMetaMed, EarlyView.
This study analyzed 236 heart failure with preserved ejection fraction (HFpEF) pharmacological trials registered on ClinicalTrials.gov from 2003 to 2025, revealing a post‐2016 surge (76.3%), U.S. dominance (58.5%), and prominence of SGLT2 inhibitors/novel therapies (each 13.1%).
Yucheng Hou, Jingwei Zhao, Yuqian Tang, Tan Liu, Zhiao Zhang, Ziheng Wang, Han Shen   +6 more
wiley   +1 more source

Structural and Computational Insights into the Angiotensin II Type 1 Receptor: Advances in Antagonist Design and Implications for Hypertension Therapy (2020-2024). [PDF]

Biomolecules
Chatzipieris FP, Petsas E, Lambrinidis G, Matsoukas JM, Mavromoustakos T.   +4 more
europepmc   +1 more source

Vascular Calcification: Mechanisms, Models, and Therapies

iNew Medicine, EarlyView.
ABSTRACT Vascular calcification represents an active multifactorial process that mirrors several key features of skeletal bone mineralization. Clinically, it is characterized by diminished arterial compliance and increased arterial wall stiffness, both of which serve as independent predictors of significant adverse cardiovascular events.
Wenya Zhu, Shu Yang, Ziyi Chen, Xiaoxiao Yang, Zhen Liang, Yuanli Chen   +5 more
wiley   +1 more source

LARP1 acts as a key mediator in preventing angiotensin II-induced cardiac dysfunction and fibrosis. [PDF]

Cell Biosci
Zheng H, Yang C.
europepmc   +1 more source

Reductions in angiotensin II type 2 receptor-mediated vasodilation contribute to increased angiotensin II vasoconstrictor sensitivity in women with preeclampsia history. [PDF]

Clin Sci (Lond)
Schwartz K, Campbell N, Jalal D, Stanhewicz A.   +3 more
europepmc   +1 more source

Angiotensin II and Atherosclerosis: A New Cardiovascular Risk Factor Beyond Hypertension. [PDF]

Int J Mol Sci
Morat N, Civieri G, Spezia M, Menegolo M, Bernava G, Iliceto S, Iop L, Tona F.   +7 more
europepmc   +1 more source

Sulfonation modification of peptides and their protective effect on angiotensin II-induced HK-2 cell injury. [PDF]

RSC Med Chem
Chen S, He S, Song S, Lin Q, He X, Jin H.   +5 more
europepmc   +1 more source