Inhibition of (pro)renin Receptor Contributes to Renoprotective Effects of Angiotensin II Type 1 Receptor Blockade in Diabetic Nephropathy [PDF]
Frontiers in Physiology, 2017 Aims: Renal renin-angiotensin system (RAS) plays a pivotal role in the development of diabetic nephropathy (DN). Angiotensin II (Ang II) type 1 receptor (AT1R) blockade elevates (pro)renin, which may bind to (pro)renin receptor (PRR) and exert receptor ...
Lin Zhang +7 more
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ANGIOTENSIN II RECEPTOR TYPE 1 EXPRESSION IN PATIENTS WITH MULTIFOCAL ATHEROSCLEROSIS
Российский кардиологический журнал, 2016 Local expression of rennin-angiotensin system (RAS) components significantly increases in patients with arterial hypertension and atherosclerosis with or without elevation of RAS activity in the blood.
I. S. Mykhailichenko
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Angiotensin II Type 1 Receptor Autoantibodies in Postural Tachycardia Syndrome
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018 BackgroundBoth the adrenergic and renin‐angiotensin systems contribute to orthostatic circulatory homeostasis, which is impaired in postural orthostatic tachycardia syndrome (POTS).
Xichun Yu +9 more
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Angiotensin-(1-9) ameliorates pulmonary arterial hypertension via angiotensin type II receptor [PDF]
The Korean Journal of Physiology & Pharmacology, 2018 Angiotensin-(1-9) [Ang-(1-9)], generated from Ang I by Ang II converting enzyme 2, has been reported to have protective effects on cardiac and vascular remodeling. However, there is no report about the effect of Ang-(1-9) on pulmonary hypertension. The aim of the present study is to investigate whether Ang-(1-9) improves pulmonary vascular remodeling ...
Seung Ah, Byung Mun Park, Suhn Hee Kim
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Novel regulations of the angiotensin II receptor type 1 by calmodulin. [PDF]
Biochem Pharmacol, 2018 Ehlers K +4 more
europepmc +2 more sources
Candesartan inhibits inflammation through an angiotensin II type 1 receptor independent way in human embryonic kidney epithelial cells [PDF]
Anais da Academia Brasileira de Ciências, 2019 : Besides stimulating vasoconstriction, Angiotensin II is also well known in inducing reactive oxygen species and promoting inflammatory phenotype switch via its type 1 receptor.
YING YU +7 more
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Effect of Angiotensin II Type 1 Receptor Blockade on Cardiac Remodeling in Angiotensin II Type 2 Receptor Null Mice [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2002 To clarify the possible involvement of uninhibited angiotensin II (Ang II) type 2 (AT 2 ) receptor stimulation in the effects of an Ang II type 1 (AT 1 ) receptor blocker, valsartan, we examined the cardiovascular remodeling induced by aortic banding with the use of wild-type ...
Lan Wu +7 more
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Telmisartan reduces systemic inflammation and alters the renin-angiotensin system in mild COVID-19 [PDF]
Scientific ReportsSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes COVID-19, a respiratory viral infection that disrupts renin angiotensin system (RAS) peptide metabolism by downregulating angiotensin converting enzyme-II (ACE2), leading to accumulation
Angela Lu +16 more
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Upregulation of NADH/NADPH oxidase 4 by angiotensin II induces podocyte apoptosis [PDF]
Kidney Research and Clinical Practice, 2023 Background Angiotensin II induces glomerular and podocyte injury via systemic and local vasoconstrictive or non-hemodynamic effects including oxidative stress. The release of reactive oxygen species (ROS) from podocytes may participate in the development
Tae-Sun Ha +3 more
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Biomedicines, 2023 The present study examined the underlying mechanisms of mechanical allodynia and thermal hyperalgesia induced by the intracisternal injection of angiotensin (Ang) II.
Ki-Don Park +8 more
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