Results 101 to 110 of about 105,823 (293)

Multiple Routes for Glutamate Receptor Trafficking: Surface Diffusion and Membrane Traffic Cooperate to Bring Receptors to Synapses [PDF]

Science's STKE (electronic resource) : signal transduction knowledge environment 327 (21/03/2006) 13, 2007
Trafficking of glutamate receptors into and out of synapses is critically involved in the plasticity of excitatory synaptic transmission. Endocytosis and exocytosis of receptors have initially been thought to account alone for this trafficking. However, membrane proteins also traffic through surface lateral diffusion in the plasma membrane. We describe
arxiv  

Alzheimer's Association clinical practice guideline for the Diagnostic Evaluation, Testing, Counseling, and Disclosure of Suspected Alzheimer's Disease and Related Disorders (DETeCD‐ADRD): Executive summary of recommendations for primary care

Alzheimer's &Dementia, EarlyView.
Abstract US clinical practice guidelines for the diagnostic evaluation of cognitive impairment due to Alzheimer's disease (AD) or AD and related dementias (ADRD) are decades old and aimed at specialists. This evidence‐based guideline was developed to empower all—including primary care—clinicians to implement a structured approach for evaluating a ...
Alireza Atri, Bradford C. Dickerson, Carolyn Clevenger, Jason Karlawish, David Knopman, Pei‐Jung Lin, Mary Norman, Chiadi Onyike, Mary Sano, Susan Scanland, Maria Carrillo   +10 more
wiley   +1 more source

Multicenter trial of olmesartan. Main results

Терапевтический архив, 2011
Development and introduction into practice of medicines reducing activity of the renin-angiotensin-aldosteron system the key element of which is angiotensin II (ATII) resulted in a significant improvement of efficacy of cardiovascular diseases treatment.
Fail' Taipovich Ageev, Ol'ga Nikolaevna Svirida, F T Ageev, O N Svirida   +3 more
doaj  

Progress in research on osteoporosis secondary to SARS‐CoV‐2 infection

Animal Models and Experimental Medicine, EarlyView.
This review explores the potential mechanisms, complications, risk factors, and future research directions related to osteoporosis secondary to SARS‐CoV‐2 infection. Key mechanisms include an imbalance between osteoclast and osteoblast activity driven by direct viral effects on bone, inflammation, hypoxia, dysregulation of noncoding RNAs, and metabolic
Jinlong Wang, Yibai Xiong, Zhiqi Song, Yanhong Li, Ling Zhang, Chuan Qin   +5 more
wiley   +1 more source

Clinical and laboratory profile and outcomes of hospitalized COVID‐19 patients with type 2 diabetes mellitus in Ghana – A single‐center study

Endocrinology, Diabetes &Metabolism, Volume 6, Issue 1, January 2023., 2023
This study describes the clinical and laboratory profile and outcomes of hospitalized COVID‐19 patients with type 2 diabetes mellitus (DM) in Ghana. Out of 175 patients (mean age 55.9+/−18.3 years) 64 (36.6%) had DM. Compared to non‐diabetics, DM patients were older (61.1? 12.8 vs. 53.0?
Yasmine Oladele Hardy, Elena Libhaber, Emmanuel Ofori, Divine Aseye Yao Amenuke, Samuel Amoabeng Kontoh, James Amoah Dankwah, Rita Larsen‐Reindorf, Caleb Otu‐Ansah, Kojo Hutton‐Mensah, Ebenezer Dadson, Sheila Adamu, Kofi Akyerekoh, Fred Stephen Sarfo, Bernard Nkum   +13 more
wiley   +1 more source

Description of unilateral kidney embolism and contralateral nephrectomy as a less invasive remnant kidney model in cats; a proof‐of‐concept study

Animal Models and Experimental Medicine, EarlyView.
Unilateral, minimally invasive, renal arterial embolization and delayed contralateral nephrectomy was described in cats as a novel remnant kidney model of chronic kidney disease using two doses of embolic particles. Renal function declined and characteristic histopathological markers of kidney disease were present 6 months after the embolism procedure.
Chad W. Schmiedt, Bianca N. Lourenço, Lauren E. Markovic, Meghan Lancaster, Sanjeev Gumber, Juliane Wannemacher, Peter Florian, Amanda E. Coleman   +7 more
wiley   +1 more source

ELECTRICAL FIELD STIMULATION OF THE RENIN ANGIOTENSIN ALDOSTERONE SYSTEM ON UTERINE SMOOTH MUSCLE

Romanian Journal of Oral Rehabilitation
Aim of the study. The permanent exchanges between the body and the environment tend to generally disturb homeostasis, particularly the hydroelectrolytic homeostasis.
Stafie Liviu, Gavrilescu Cristina Maria, Cojocaru Tudor, Panzariu Giulia Mihaela, Oprisa Cristina, Pohaci Antonesei Catalin, Forna Norin, Barbu Roxana Mihaela   +7 more
doaj   +1 more source

Angiotensin II Vascular Receptors: Their Avidity in Relationship to Sodium Balance, the Autonomic Nervous System, and Hypertension [PDF]

, 1972
Hans R. Brunner, Paul Chang, Ronald Wallach, Jean E. Sealey, John H. Laragh   +4 more
openalex   +1 more source

Silylation of Aryl and Alkyl Chlorides by a Seven‐Membered Dialkoxysilyl Group Si(pan)Me via an In Situ Generated Silylpotassium

Angewandte Chemie International Edition, EarlyView.
This study reveals a facile silylation protocol that enables the delivery of a stable and activatable dioxasilepanyl group, Si(pan)Me, to aryl and alkyl chlorides. Of note is the X‐ray structure of 18‐C‐6·K–Si(pan)Me, which elucidates a pivotal silylpotassium intermediate.
Kenshiro Hitoshio, Jun Shimokawa, Hideki Yorimitsu   +2 more
wiley   +1 more source

Angiotensin II Receptor Antagonists and Hypertension

Clinical and Experimental Hypertension, 1999
Over recent years, a number of imidazole derivatives that specifically bind to the angiotensin II type 1 receptor, thereafter called sartans, have been developed and made available to the clinician. Whether targeting antihypertensive treatment with such a high specificity within the renin cascade may carry major clinical advantage over inhibiting ...
Jean Ribstein, Guilhem DuCailar, Albert Mimran   +2 more
openaire   +2 more sources