Results 21 to 30 of about 160,198 (339)

Potential use of angiotensin receptor blockers in skin pathologies [PDF]

Iranian Journal of Basic Medical Sciences, 2023
Renin-angiotensin system (RAS) components such as angiotensin II, angiotensin receptors (AT1R and AT2R), and angiotensin-converting enzyme (ACE) are expressed in different cell types of the skin.
Keshvad Hedayatyanfard, Azadeh Khalili, Hosein Karim, Soren Nooraei, Ehsan Khosravi, Nazgol Sadat Haddadi, Ahmad Reza Dehpour, Gholamreza Bayat   +7 more
doaj   +1 more source

In Vitro Characterization of a Tissue Renin-Angiotensin System in Human Nucleus Pulposus Cells

Cells, 2022
Low back pain is a clinically highly relevant musculoskeletal burden and is associated with inflammatory as well as degenerative processes of the intervertebral disc.
Babak Saravi, Zhen Li, Valentina Basoli, Sibylle Grad, Sonja Häckel, Christoph E. Albers, Mauro Alini, Hagen Schmal, Peter Obid, Gernot Lang   +9 more
doaj   +1 more source

The hyperglycemia induced by angiotensin II in rats is mediated by AT1 receptors

Brazilian Journal of Medical and Biological Research, 1998
We have shown that the renin-angiotensin system (RAS) is involved in glucose homeostasis during acute hemorrhage. Since almost all of the physiological actions described for angiotensin II were mediated by AT1 receptors, the present experiments were ...
L.J.C. Machado, U. Marubayashi, A.M. Reis, C.C. Coimbra   +3 more
doaj   +1 more source

The effect of losartan on angiotensin II-induced cell proliferation in a rat aorta smooth muscle cell line

Brazilian Archives of Biology and Technology, 2012
The success of revascularization procedures is limited by recurrent stenosis, which is a narrowing of a blood vessels that results from neo-intimal hyperplasia.
Natália Tambelline, Karen Oliveira, Luiz Renato Olchanheski Junior, Regina Sordi, Michel Fleith Otuki, Giovani Marino Favero, Daniel Fernandes   +6 more
doaj   +1 more source

G protein coupled receptors of the renin-angiotensin system: new targets against breast cancer?

Frontiers in Pharmacology, 2015
G-protein coupled receptors (GPCRs) constitute the largest family of membrane receptors, with high potential for drug discovery. These receptors can be activated by a panel of different ligands including ions, hormones, small molecules and vasoactive ...
Clara eNAHMIAS, Sylvie eRODRIGUES-FERREIRA   +1 more
doaj   +1 more source

From Living in Saltwater to a Scarcity of Salt and Water, and Then an Overabundance of Salt—The Biological Roller Coaster to Which the Renin–Angiotensin System Has Had to Adapt: An Editorial

Biomedicines, 2023
Angiotensin II (Ang II) is a hormone with much more complex actions than is typical for other agonists with heterotrimeric G protein-coupled receptors (GPCRs) [...]
György L. Nádasy, András Balla, Mária Szekeres   +2 more
doaj   +1 more source

Angiotensin II and VEGF are Involved in Angiogenesis Induced by Short-Term Exercise Training [PDF]

, 2001
Results from our laboratory have suggested a pathway involving angiotensin II type 1 (AT1) receptors and vascular endothelial growth factor (VEGF) in angiogenesis induced by electrical stimulation.
Amaral, Sandra L., Greene, Andrew S., Papanek, Paula   +2 more
core   +2 more sources

Differential mechanisms of activation of the Ang peptide receptors AT1, AT2, and MAS: using in silico techniques to differentiate the three receptors.

PLoS ONE, 2013
The renin-angiotensin system is involved in multiple conditions ranging from cardiovascular disorders to cancer. Components of the pathway, including ACE, renin and angiotensin receptors are targets for disease treatment.
Jeremy W Prokop, Robson A S Santos, Amy Milsted   +2 more
doaj   +1 more source

Actions of Novel Angiotensin Receptor Blocking Drugs, Bisartans, Relevant for COVID-19 Therapy: Biased Agonism at Angiotensin Receptors and the Beneficial Effects of Neprilysin in the Renin Angiotensin System

Molecules, 2022
Angiotensin receptor blockers (ARBs) used in the treatment of hypertension and potentially in SARS-CoV-2 infection exhibit inverse agonist effects at angiotensin AR1 receptors, suggesting the receptor may have evolved to accommodate naturally occurring ...
Graham J. Moore, Harry Ridgway, Konstantinos Kelaidonis, Christos T. Chasapis, Irene Ligielli, Thomas Mavromoustakos, Joanna Bojarska, John M. Matsoukas   +7 more
doaj   +1 more source

INACTIVATION OF RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM. WHICH CLASS OF ANTIHYPERTENSIVE MEDICINE PRODUCTS TO PREFER?

Евразийский Кардиологический Журнал, 2020
A comparative analysis of the effectiveness of two classes of drugs – angiotensin converting enzyme inhibitors (ACEI) and angiotensin II type 1 receptor blockers (ARBS II) in the prevention of cardiovascular diseases is presented.
S. V. Stolov
doaj   +1 more source