Results 311 to 320 of about 183,644 (348)

Expression of type 1 angiotensin II receptors in human aldosteronomas

Endocrine Research, 1995
Type 1 angiotensin II (AII) receptors (AT1 receptors), besides stimulation of aldosterone secretion, seem to transduce the growth factor-like activity of AII on glomerulosa cells. Although a local renin-angiotensin system and AII synthesis have been found in human adrenals and aldosteronomas, it is unclear whether aldosteronomas express AT1 receptors ...
R. SARZANI, OPOCHER, GIUSEPPE, P. DESSIFULGHERI, V. PACI, G. COLA, S. ROCCO, B. VIANELLO, MANTERO, FRANCO, A. RAPPELLI   +8 more
openaire   +2 more sources

The Angiotensin II Type 1 Receptor Antagonists

Archives of Internal Medicine, 1995
The angiotensin II (AII) type 1 receptor antagonists represent a new pharmacologic class of drugs that are specifically designed to displace All from its type 1 receptor subtype. These drugs antagonize AII-induced biologic actions, including smooth-muscle contraction, sympathetic pressor mechanisms, and aldosterone release.
openaire   +1 more source

PP085. Angiotensin II type 1 receptor antibodies increase angiotensin II sensitivity in pregnant rats

Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health, 2012
Pregnant women who subsequently develop preeclampsia are highly sensitive to infused angiotensin (Ang) II; the sensitivity persists postpartum. Activating autoantibodies against the Ang II type 1 (AT1) receptor are present in preeclampsia. In vitro and in vivo data suggest that they could be involved in the disease process.The aim of the study was to ...
K, Wenzel, F, Herse, A, Rajakumar, H, Haase, C A, Hubel, G, Wallukat, R, Pijnenborg, D N, Muller, B B, LaMarca, R, Dechend   +9 more
openaire   +2 more sources

Regulation of angiotensin II type 1 (AT1) receptor function

Regulatory Peptides, 1999
The type 1 angiotensin receptor (AT1) mediates the important biological actions of the peptide hormone, angiotensin II (AngII), by activating an array of intracellular signaling pathways. The unique temporal arrangement and duration of AngII-stimulated signals suggests a hierarchy of post-AT1 receptor binding events that permits activation of selective
openaire   +3 more sources

Angiotensin II type 1 receptor antagonists

Biochemical Pharmacology, 2000
Patrick M.L Vanderheyden, Frederik L.P Fierens, Georges Vauquelin   +2 more
openaire   +1 more source

Cloning and expression of a complementary DNA encoding a bovine adrenal angiotensin II type-1 receptor

Nature, 1991
K. Sasaki, Y. Yamano, S. Bardhan, N. Iwai, J. Murray, M. Hasegawa, Yuzuru Matsudat, Tadashi lnagami   +7 more
semanticscholar   +1 more source

[Mechanisms underlying angiotensin II-independent activation of angiotensin II type 1 receptor].

Nihon rinsho. Japanese journal of clinical medicine, 2012
A growing body of evidence indicates that activation of angiotensin II (Ang II) type 1 (AT1) receptor, a seven -transmembrane G protein -coupled receptor, is critically involved in the development of various cardiovascular diseases. Inherently, AT1 receptor is structurally unstable, and shows spontaneous constitutive activity in an Ang II-independent ...
Hiroshi, Akazawa, Issei, Komuro
openaire   +1 more source

Cardioprotective Angiotensin-(1–7) Peptide Acts as a Natural-Biased Ligand at the Angiotensin II Type 1 Receptor

HYPERTENSION, 2016
Ségolène Galandrin, C. Denis, C. Boularan, J. Marie, Céline M'kadmi, Claire Pilette, C. Dubroca, Yvan Nicaise, M. Séguélas, Du N’Guyen, J. Banères, A. Pathak, J. Sénard, C. Galés   +13 more
semanticscholar   +1 more source

Systemic therapy for hormone receptor‐positive/human epidermal growth factor receptor 2‐negative early stage and metastatic breast cancer

Ca-A Cancer Journal for Clinicians, 2023
Laura A Huppert, Hope S Rugo
exaly  

A Systematic Comparison of the Properties of Clinically Used Angiotensin II Type 1 Receptor Antagonists

Pharmacological Reviews, 2013
M. C. Michel, C. Foster, H. Brunner, Li-sheng Liu   +3 more
semanticscholar   +1 more source