Results 21 to 30 of about 2,636,203 (317)

ACE (Angiotensin-Converting Enzyme) Inhibitors/Angiotensin Receptor Blockers Are Associated With Lower Colorectal Cancer Risk

open access: yesHYPERTENSION, 2020
Supplemental Digital Content is available in the text. Whether ACE (angiotensin-converting enzyme) inhibitors and angiotensin receptor blockers modify colorectal cancer risk remains controversial.
K. Cheung   +4 more
semanticscholar   +1 more source

Roles and functions of Atp6ap2 in the brain

open access: yesNeural Regeneration Research, 2018
The classical renin-angiotensin system (RAS) in the body has been studied intensively in the last decades, since it is known that this system is involved in the regulation of blood pressure.
Alexander Bracke   +1 more
doaj   +1 more source

Angiotensin Receptor-Neprilysin Inhibition (ARNI) in Heart Failure

open access: yesInternational Journal of Heart Failure, 2020
Recognition that neurohormonal activation plays a central role in the pathogenesis of heart failure (HF) led to the development of angiotensin converting enzyme inhibitors (ACEIs), angiotensin receptor blockers, mineralocorticoid receptor antagonists and
B. Greenberg
semanticscholar   +1 more source

Des-Aspartate-Angiotensin I Attenuates Mortality of Mice Exposed to Gamma Radiation via a Novel Mechanism of Action. [PDF]

open access: yesPLoS ONE, 2015
ACE inhibitors and ARBs (angiotensin receptor blockers) have been shown to attenuate radiation injuries in animal models of lethal gamma irradiation. These two classes of drug act by curtailing the actions of angiotensin II-linked inflammatory pathways ...
Hong Wang   +3 more
doaj   +1 more source

ACE inhibitors, angiotensin receptor blockers and endothelial injury in COVID‐19

open access: yesJournal of Internal Medicine, 2020
COVID‐19 is caused by the coronavirus SARS‐CoV‐2, which uses angiotensin‐converting enzyme 2 (ACE‐2) as a receptor for cellular entry. It is theorized that ACE inhibitors (ACE‐Is) or angiotensin receptor blockers (ARBs) may increase vulnerability to SARS‐
S. Tetlow   +17 more
semanticscholar   +1 more source

Synthetic nanobodies as angiotensin receptor blockers

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2020
Significance The G protein-coupled receptor (GPCR) family is responsible for regulating much of human physiology, and GPCRs have become the most successful target class for drug development.
Conor McMahon   +9 more
semanticscholar   +1 more source

Angiotensin‐converting enzyme inhibitors and angiotensin II receptor blockers are not associated with severe COVID‐19 infection in a multi‐site UK acute hospital trust

open access: yesEuropean Journal of Heart Failure, 2020
The SARS‐CoV‐2 virus binds to the angiotensin‐converting enzyme 2 (ACE2) receptor for cell entry. It has been suggested that angiotensin‐converting enzyme inhibitors (ACEi) and angiotensin II receptor blockers (ARB), which are commonly used in patients ...
D. Bean   +13 more
semanticscholar   +1 more source

Influence of myocardial infarction on changes in the expression of angiotensin type 1 receptor in the rat prostate

open access: yesFolia Histochemica et Cytobiologica, 2011
Angiotensin II (AngII) is the biologically active peptide of the renin-angiotensin system (RAS). Tissue- based, local RAS has been identified in the prostate, testis, epididymis and coagulating glands.
Kamila Domińska   +5 more
doaj   +1 more source

ACE2 (Angiotensin-Converting Enzyme 2), COVID-19, and ACE Inhibitor and Ang II (Angiotensin II) Receptor Blocker Use During the Pandemic

open access: yesHYPERTENSION, 2020
Potential but unconfirmed risk factors for coronavirus disease 2019 (COVID-19) in adults and children may include hypertension, cardiovascular disease, and chronic kidney disease, as well as the medications commonly prescribed for these conditions, ACE ...
A. South, T. Brady, J. Flynn
semanticscholar   +1 more source

Influence of angiotensin II receptor blocker combination tablet prescription on drug number and cost

open access: yesSAGE Open Medicine, 2014
Objectives: Combination therapy using an angiotensin II receptor blocker is expected to promote medication adherence and alleviate economic burden among patients by reducing the number of drugs taken, and thereby to lower associated medical costs. In the
Hitomi Teramachi   +8 more
doaj   +1 more source

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