Results 51 to 60 of about 2,811,792 (409)
Biomedicines, 2022 Recent studies have shown that fascial fibroblasts are sensitive to different stimuli (biochemical or biophysical), promoting extracellular matrix remodeling, as well as synthetic activity.
Carmelo Pirri +8 more
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Tumor Biology, 2017 Local migration and long-distance metastasis is the main reason for higher mortality of ovarian cancer. Microtubule-associated tumor suppressor 1/angiotensin II type 2 receptor–interacting protein is associated with tumor initiation and progression and ...
Ping Huang +3 more
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Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018 BackgroundThe classical renin‐angiotensin system is known as the angiotensin (Ang)‐converting enzyme/Ang II/Ang type 1 receptor axis, which induces various organ damage including cognitive decline.
Akinori Higaki +12 more
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Role of vascular smooth muscle PPARγ in regulating AT1 receptor signaling and angiotensin II-dependent hypertension. [PDF]
PLoS ONE, 2014 Peroxisome proliferator activated receptor γ (PPARγ) has been reported to play a protective role in the vasculature; however, the underlying mechanisms involved are not entirely known.
Maria Alicia Carrillo-Sepulveda +4 more
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Structural basis of receptor recognition by SARS-CoV-2
Nature, 2020 A novel severe acute respiratory syndrome (SARS)-like coronavirus (SARS-CoV-2) recently emerged and is rapidly spreading in humans, causing COVID-19 1 , 2 . A key to tackling this pandemic is to understand the receptor recognition mechanism of the virus,
J. Shang +8 more
semanticscholar +1 more source
PPAR Research, 2020 The activation of the renin-angiotensin system (RAS) participates in the development of metabolic syndrome (MetS) and in heart failure. PPAR-alpha activation by fenofibrate reverts some of the effects caused by these pathologies.
María Sánchez-Aguilar +7 more
doaj +1 more source
Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus
Nature, 2003 Spike (S) proteins of coronaviruses, including the coronavirus that causes severe acute respiratory syndrome (SARS), associate with cellular receptors to mediate infection of their target cells. Here we identify a metallopeptidase, angiotensin-converting
Wenhui Li +11 more
semanticscholar +1 more source
Angiotensin Receptor Blockers [PDF]
High Blood Pressure & Cardiovascular Prevention, 2003 Angiotensin receptor blockers (also known as ARBs) are a class of medications that are widely used by patients with high blood pressure, kidney disease, and heart failure. This article provides information for patients who receive this type of medication.
M Ruilope, Massimo Volpe
openaire +2 more sources
Next Step in Chronic Kidney Disease Therapy
Počki, 2016 Angiotensin-converting enzyme inhibitors/angiotensin receptor blockers are the basis of renoprotection therapy in chronic kidney disease. Parallel to decrease of glomerular filtration rate, there is an increase in the activity of the sympathetic nervous ...
D.D. Ivanov
doaj +1 more source
Case Reports in Nephrology, 2020 The renin-angiotensin system plays a very critical role in hypertension, diabetes, and kidney and heart diseases. The blockade of the renin-angiotensin system results in the prevention of progression of renal and cardiac damage.
Avantika Chenna +7 more
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