Results 51 to 60 of about 200,791 (194)
Quantum Optical Immunoassay: Upconversion Nanoparticle-based Neutralizing Assay for COVID-19 [PDF]
arXiv, 2021 In a viral pandemic, a few important tests are required for successful containment of the virus and reduction in severity of the infection. Among those tests, a test for the neutralizing ability of an antibody is crucial for assessment of population immunity gained through vaccination, and to test therapeutic value of antibodies made to counter the ...
arxiv
ATRQβ‐001 Vaccine Prevents Experimental Abdominal Aortic Aneurysms
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019 Background We have developed a peptide vaccine named ATRQβ‐001, which was proved to retard signal transduction initiated by angiotensin II (Ang II). Ang II was implicated in abdominal aortic aneurysm (AAA) progression, but whether the ATRQβ‐001 vaccine ...
Hongrong Zhang +12 more
doaj +1 more source
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019 Background Angiotensin II type 1 receptor (AT1R) autoantibody (AT1‐AA) was first identified as a causative factor in preeclampsia. Unlike physiological ligand angiotensin II (Ang II), AT1‐AA can induce vasoconstriction in a sustained manner, causing a ...
Jingwei Bian +9 more
doaj +1 more source
The modelling of COVID19 pathways sheds light on mechanisms, opportunities and on controversial interpretations of medical treatments. v2 [PDF]
arXiv, 2020 The new coronavirus (2019-nCoV or SARS-CoV2), inducing the current pandemic disease (COVID-19) and causing pneumoniae in humans, is dramatically increasing in epidemic scale since its first appearance in Wuhan, China, in December 2019. The first infection from epidemic coronaviruses in 2003 fostered the spread of an overwhelming amount of related ...
arxiv
Persistent topological Laplacian analysis of SARS-CoV-2 variants [PDF]
arXiv, 2023 Topological data analysis (TDA) is an emerging field in mathematics and data science. Its central technique, persistent homology, has had tremendous success in many science and engineering disciplines. However, persistent homology has limitations, including its incapability of describing the homotopic shape evolution of data during filtration ...
arxiv
Angiotensin Receptors, Autoimmunity, and Preeclampsia [PDF]
The Journal of Immunology, 2007 Abstract Preeclampsia is a pregnancy-induced hypertensive disorder that causes substantial maternal and fetal morbidity and mortality. Despite being a leading cause of maternal death and a major contributor to maternal and perinatal morbidity, the mechanisms responsible for the pathogenesis of preeclampsia are poorly understood.
Rodney E. Kellems +3 more
openaire +3 more sources
Effect of Angiotensin II on Blood Flow in Acute and Chronically Inflamed Knee Joints of Rabbits: The Role of Nitric Oxide [PDF]
Iranian Journal of Medical Sciences, 2009 Background: Angiotensin converting enzyme (ACE) upregulationin stromal cells of joints affected by rheumatoid arthritismay lead to higher tissue angiotensin II that is a vasoconstrictorand mitogen factor.
Hamid Najafipour +3 more
doaj
Mutations strengthened SARS-CoV-2 infectivity [PDF]
arXiv, 2020 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infectivity is a major concern in coronavirus disease 2019 (COVID-19) prevention and economic reopening. However, rigorous determination of SARS-COV-2 infectivity is essentially impossible owing to its continuous evolution with over 13752 single nucleotide polymorphisms (SNP) variants in six ...
arxiv
Clinical dichotomania: A major cause of over-diagnosis and over-treatment? [PDF]
arXiv, 2023 Introduction: There have been many warnings that inappropriate dichotomisation of results into positive or negative, high, or normal etc., during medical research could be very damaging. The aim of this paper is to argue that this is the main cause of over-diagnosis and over-treatment.
arxiv
Hypertension regulating angiotensin peptides in the pathobiology of cardiovascular disease
Clinical and Experimental Hypertension, 2018 Renin angiotensin system (RAS) is an endogenous hormone system involved in the control of blood pressure and fluid volume. Dysregulation of RAS has a pathological role in causing cardiovascular diseases through hypertension.
Misbah Hussain, Fazli Rabbi Awan
doaj +1 more source