Results 61 to 70 of about 200,791 (194)
Oxidative DNA damage in kidneys and heart of hypertensive mice is prevented by blocking angiotensin II and aldosterone receptors. [PDF]
PLoS ONE, 2014 INTRODUCTION: Recently, we could show that angiotensin II, the reactive peptide of the blood pressure-regulating renin-angiotensin-aldosterone-system, causes the formation of reactive oxygen species and DNA damage in kidneys and hearts of hypertensive ...
Susanne Brand +4 more
doaj +1 more source
Modelling and docking of Indian SARS-CoV-2 spike protein 1 with ACE2: implications for co-morbidity and therapeutic intervention [PDF]
arXiv, 2020 Presently, India bears amongst the highest burden of non-communicable diseases such as diabetes mellitus (DM), hypertension (HT), and cardio vascular disease (CVD) and thus represents a vulnerable target to the SARS-CoV-2/COVID-19 pandemic. Involvement of the angiotensin converting enzyme 2 (ACE2) in susceptibility to infection and pathogenesis by SARS-
arxiv
Revista Colombiana de Obstetricia y Ginecología, 2011 Introducción: el cáncer de mama es el segundo casos y 50 controles y se genotipificaron los tipo de cáncer más común y la quinta causa de muerte por cáncer a nivel mundial.
Andrés Felipe Castro D +3 more
doaj
A computational insight of the improved nicotine binding with ACE2-SARS-CoV-2 complex with its clinical impact [PDF]
arXiv, 2020 Smokers being witnessed with the mild adverse clinical symptoms of SARS-CoV-2, the in-silico study is intended to explore the effect of nicotine binding to the soluble angiotensin converting enzyme II (ACE2) receptor with or without SARS-CoV-2 binding.
arxiv
Angiotensin Receptors and Aging [PDF]
Hypertension, 2007 The major biological actions of the renin–angiotensin system are mediated by angiotensin (Ang) II, which binds with equal affinity to Ang type 1 (AT1) and type 2 (AT2) receptors. The majority of Ang II actions, however, are mediated by the AT1 receptor, including vasoconstriction, cellular proliferation, tissue growth, direct renal tubular sodium ...
openaire +2 more sources
Angiotensin Ii Receptor Blockers [PDF]
Baylor University Medical Center Proceedings, 2003 The ARBs have very similar clinical profiles. They do, however, have different pharmacokinetic profiles, which may lead to some differences in efficacy. The newer agents irbesartan, candesartan, telmisartan, and olmesartan have longer half-lives and durations of action than the older agents losartan and valsartan (5).
Cheryle Gurk-Turner, Amy Barreras
openaire +3 more sources
ANGIOTENSIN II RECEPTOR TYPE 1 EXPRESSION IN PATIENTS WITH MULTIFOCAL ATHEROSCLEROSIS
Российский кардиологический журнал, 2016 Local expression of rennin-angiotensin system (RAS) components significantly increases in patients with arterial hypertension and atherosclerosis with or without elevation of RAS activity in the blood.
I. S. Mykhailichenko
doaj +1 more source
Role of Nonclassical Renin-angiotensin system Axis In Renal Fibrosis
Frontiers in Physiology, 2015 The renin–angiotensin system (RAS) is a major regulator of renal fibrosis. Besides the classical renin/Angiotensin-converting enzyme 2 (ACE2)/angiotensin II (Ang II)/AT1 and AT2 axis, multiple new axes have been recently described.
Linli eLv, Bi-Cheng eLiu
doaj +1 more source
Review of COVID-19 Antibody Therapies [PDF]
arXiv, 2020 Under the global health emergency caused by coronavirus disease 2019 (COVID-19), efficient and specific therapies are urgently needed. Compared with traditional small-molecular drugs, antibody therapies are relatively easy to develop and as specific as vaccines in targeting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and thus attract ...
arxiv
Fimasartan: A new armament to fight hypertension
Journal of Family Medicine and Primary Care, 2019 Hypertension is a major public health problem of modern era. Fimasartan is a new Angiotensin Receptor Blocker approved for treatment of hypertension.
Akshyaya Pradhan +2 more
doaj +1 more source