Results 61 to 70 of about 2,811,792 (409)

Therapeutic potential of the renin angiotensin system in ischaemic stroke [PDF]

open access: yes, 2016
The renin angiotensin system (RAS) consists of the systemic hormone system, critically involved in regulation and homeostasis of normal physiological functions [i.e.
Arroja, Mariana Moreira Coutinho   +2 more
core   +1 more source

Hypertension Hot Potato - Anatomy of the Angiotensin-Receptor Blocker Recalls.

open access: yesNew England Journal of Medicine, 2019
Hypertension Hot Potato A spate of recalls of angiotensin-receptor blockers highlights several issues related to the readiness of our health systems to respond to drug recalls, trust between patients and providers, uncertain drug-dose equivalences, and ...
J. B. Byrd, G. Chertow, Vivek Bhalla
semanticscholar   +1 more source

Intraoperative angioedema induced by angiotensin II receptor blocker: a case report

open access: yesPatient Safety in Surgery, 2018
Background Angiotensin II receptor blockers are a class of antihypertensive agent that is developed to exclude the adverse effects of angiotensin converting enzyme inhibitors.
Ala”a Alhowary   +3 more
doaj   +1 more source

Novel Pharmacology Following Heteromerization of the Angiotensin II Type 2 Receptor and the Bradykinin Type 2 Receptor

open access: yesFrontiers in Endocrinology, 2022
The angiotensin type 2 (AT2) receptor and the bradykinin type 2 (B2) receptor are G protein-coupled receptors (GPCRs) that have major roles in the cardiovascular system. The two receptors are known to functionally interact at various levels, and there is
Elizabeth K. M. Johnstone   +15 more
doaj   +1 more source

Use of Antihypertensive Agents and Association With Risk of Adverse Outcomes in Chronic Kidney Disease: Focus on Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers. [PDF]

open access: yes, 2018
Background Our objective was to determine patterns of antihypertensive agent use by stage of chronic kidney disease (CKD) and to evaluate the association between different classes of antihypertensive agents with nonrenal outcomes, especially in advanced ...
Johansen, Kirsten L   +4 more
core  

Resetting the neurohormonal balance in heart failure (HF). the relevance of the natriuretic peptide (NP) system to the clinical management of patients with HF [PDF]

open access: yes, 2017
The natriuretic peptide (NP) system, which includes atrial natriuretic peptide, B-type natriuretic peptide, and C-type natriuretic peptide, has an important role in cardiovascular homeostasis, promoting a number of physiological effects including ...
Rubattu, Speranza Donatella   +1 more
core   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Association Between Angiotensin-Converting Enzyme Inhibitors, Angiotensin Receptor Blockers, and Suicide

open access: yesJAMA Network Open, 2019
Key Points Question Are angiotensin receptor blockers associated with a higher risk of suicide than angiotensin-converting enzyme inhibitors? Findings In this case-control study of 964 older adults who died by suicide and 3856 matched control ...
M. Mamdani   +7 more
semanticscholar   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

open access: yesFEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani   +7 more
wiley   +1 more source

ACE-2 receptor-associated COVID-19 lesions and sequelae

open access: yesMexican Journal of Medical Research ICSA, 2023
La infección por el nuevo SARS-CoV 2 se ha convertido en el mayor problema de salud pública mundial desde la aparición de la enfermedad en 2019 en China; A partir de ese momento, la comunidad médica y científica se ha enfocado en describir los mecanismos
Marco A. Becerril-Flores   +4 more
doaj   +1 more source

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