Results 81 to 90 of about 200,791 (194)

Editorial: Emerging receptors as new targets in health and disease

Frontiers in Endocrinology, 2022
Julie Dam, Julien Hanson, Julien Hanson, Martyna Szpakowska   +3 more
doaj   +1 more source

Insights into new mechanosensitive behaviors of G protein-coupled receptors [PDF]

arXiv
G protein-coupled receptors (GPCRs) represent a diverse and vital family of membrane proteins that mediate intracellular signaling in response to extracellular stimuli, playing critical roles in physiology and disease. Traditionally recognized as chemical signal transducers, GPCRs have recently been implicated in mechanotransduction, the process of ...
arxiv  

Advances in the Renin-Angiotensin-Aldosterone System: Relevance to Diabetic Nephropathy

The Scientific World Journal, 2008
Hypertension is now recognized as a key contributory factor to the development and progression of kidney disease in both type 1 and type 2 diabetes. The renin angiotensin system (RAS) and its effector molecule angiotensin II, in particular, have a range ...
Audrey Koitka, Christos Tikellis
doaj   +1 more source

Rapid response to fast viral evolution using AlphaFold 3-assisted topological deep learning [PDF]

arXiv
The fast evolution of SARS-CoV-2 and other infectious viruses poses a grand challenge to the rapid response in terms of viral tracking, diagnostics, and design and manufacture of monoclonal antibodies (mAbs) and vaccines, which are both time-consuming and costly. This underscores the need for efficient computational approaches.
arxiv  

Angiotensin-Receptor Blockers Prevent Vestibular Schwannoma-Associated Hearing Loss. [PDF]

Otol Neurotol
Early S, Brown A, Xu L, Stankovic KM.
europepmc   +1 more source

Angiotensin Receptor Neprilysin Inhibition: An Overlooked Frontier in the Treatment of Hypertension. [PDF]

JACC Asia
Wijkman MO.
europepmc   +1 more source

Intranasal administration of angiotensin receptor shRNA to brain lowers blood pressure in spontaneously hypertensive rats. [PDF]

Biomed Pharmacother
Lamptey RNL, Sun C, Singh J.
europepmc   +1 more source

In-hospital initiation of angiotensin receptor-neprilysin inhibition in acute heart failure: the PREMIER trial. [PDF]

Eur Heart J
Tanaka A, Kida K, Matsue Y, Imai T, Suwa S, Taguchi I, Hisauchi I, Teragawa H, Yazaki Y, Moroi M, Ohashi K, Nagatomo D, Kubota T, Ijichi T, Ikari Y, Yonezu K, Takahashi N, Toyoda S, Toshida T, Suzuki H, Minamino T, Nogi K, Shiina K, Horiuchi Y, Tanabe K, Hachinohe D, Kiuchi S, Kusunose K, Shimabukuro M, Node K.   +29 more
europepmc   +1 more source

Left ventricular function improvement during angiotensin receptor-neprilysin inhibitor treatment in a cohort of HFrEF/HFmrEF patients. [PDF]

ESC Heart Fail
Appenzeller F, Harm T, Sigle M, Aidery P, Kreisselmeier KP, Baas L, Goldschmied A, Gawaz MP, Müller KAL.   +8 more
europepmc   +1 more source

Potential renoprotective effects and possible underlying mechanisms of angiotensin receptor-neprilysin inhibitors in cardiorenal syndrome. [PDF]

Front Med (Lausanne)
Rahman MM, Rahman A, Nishiyama A.
europepmc   +1 more source