A computational insight of the improved nicotine binding with ACE2-SARS-CoV-2 complex with its clinical impact [PDF]
Smokers being witnessed with the mild adverse clinical symptoms of SARS-CoV-2, the in-silico study is intended to explore the effect of nicotine binding to the soluble angiotensin converting enzyme II (ACE2) receptor with or without SARS-CoV-2 binding.
arxiv
Novel pathways of heart failure with preserved ejection fraction [PDF]
INTRODUCTION: Diastolic heart failure (HF) i.e., HF with preserved ejection fraction (HFpEF) accounts for ~50% of all clinical HF presentations; but unlike systolic HF i.e., HF with reduced ejection fraction (HFrEF), there are no evidenced based ...
Li, Shanpeng
core +1 more source
Evidence for regulatory diversity and auto-regulation at the TAC1 locus in sensory neurones [PDF]
Peer reviewedPublisher ...
Davidson, Scott+4 more
core +4 more sources
Real Time Hemodynamic Monitoring During M‐TEER Using Electrical Cardiometry
ABSTRACT Background Mitral regurgitation is a common valvular dysfunction causing patient morbidity and mortality. Mitral transcatheter edge‐to‐edge repair (M‐TEER) allows grasping of valvular leaflets and approximation via a small implant, thus reducing mitral regurgitation (MR).
Andreas Goldschmied+6 more
wiley +1 more source
Despite improved prognosis in patients with heart failure (HF) treated with neurohumoral activation-suppressing drugs (such as angiotensin-converting enzyme inhibitors, angiotensin II receptor antagonists, Β-adrenergic receptor antagonists, aldosterone ...
I V Zhirov+3 more
doaj
PLACE OF ANGIOTENSIN II RECEPTOR ANTAGONISTS IN ARTERIAL HYPERTENSION THERAPY
Angiotensin II receptor antagonists (ARA) established their position recently duet to new indications above arterial hypertension (HT). These are chronic heart failure, history of myocardial infarction, atrial fibrillation and metabolic syndrome ...
S. A. Boytsov, I. P. Kolos
doaj +1 more source
Synergistic effects of cardiac resynchronization therapy and drug up-titration in heart failure. is this enough? [PDF]
This editorial refers to ‘Optimization of heart failure medication after cardiac resynchronization therapy and the impact on long-term survival’, by C.T.
FRANCIA, Pietro, VOLPE, Massimo
core +1 more source
Contemporary Perspectives on Chronic Renal Disorders
ABSTRACT The prevalence of renal diseases and its associated burden on healthcare have tremendously risen in the past few years. From simple markers assessing kidney function, current renal research delves into understanding the diseases at the cellular and molecular levels and not just at treating, but at improving quality of life, arresting ...
Deenadhayalan Ashok+5 more
wiley +1 more source
Beta-blockers and inhibitors of the renin-angiotensin aldosterone system for chronic heart failure with preserved ejection fraction [PDF]
This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To evaluate the safety and efficacy of beta-blockers (BBs), angiotensin converting enzyme inhibitors (ACEIs), angiotensin receptor antagonists (ARBs ...
Casas, JP+6 more
core +1 more source
Autosomal dominant polycystic kidney disease is the most prevalent inherited kidney disease and leads to bilateral kidney enlargement and progressive loss of renal function, often over decades. Comorbidities include hypertension, flank pain, and bacterial infections. The condition often necessitates prolonged multidrug therapy.
Annika C. Tillmann+6 more
wiley +1 more source