Results 241 to 250 of about 444,347 (295)

Overview of angiotensin II-receptor antagonists

The American Journal of Cardiology, 1998
T renin–angiotensin system is integral to the mechanisms that regulate cardiovascular homeostasis. The renin–angiotensin system has an important role in the pathophysiology of hypertension and heart failure via the vasoconstricting effects of angiotensin II, which sustain elevated blood pressure levels in hypertension and increase afterload in chronic ...
B, Pitt, M A, Konstam
openaire   +2 more sources

Angiotensin II receptor antagonists.

Arzneimittel-Forschung, 1993
The development of novel non-peptide compounds with high affinity for-angiotensin II (Ang II) receptors has greatly facilitated the subclassification of Ang II receptors into AT1- and AT2-receptor subtypes. Whereas PD 123177 (1-(4-amino-3-methylphenyl)methyl-5-diphenyl-acetyl-4,5,6,7-tetrahydro- 1H-imidazol [4,5-c]pyridine-6-carboxylic acid) is the ...
J C, van Meel, M, Entzeroth, N, Hauel, B, Narr, U, Ries, W, Wienen   +5 more
openaire   +1 more source

Angiotensin-Converting Enzyme Inhibitors and Angiotensin II Receptor Antagonists

Archives of Otolaryngology–Head & Neck Surgery, 2004
The use of angiotensin-converting enzyme inhibitors (ACEIs) has been implicated in many cases of angioedema, but, given the potential mechanism of this complication, it was not expected to be caused by angiotensin II receptor blockers (ARBs). However, in the past few years, scattered reports of angioedema associated with ARBs have appeared in the ...
Dionysios E, Kyrmizakis, Chariton E, Papadakis, Antonios D, Liolios, Alexandros D, Karatzanis, Stylianos, Malandrakis, Charalambos E, Skoulakis, John G, Bizakis, George A, Velegrakis   +7 more
openaire   +2 more sources

Insurmountable angiotensin AT1 receptor antagonists: the role of tight antagonist binding

European Journal of Pharmacology, 1999
Angiotensin II increased the inositol phosphates production (EC50 = 3.4+/-0.7 nM) in Chinese hamster ovary (CHO) cells expressing the cloned human angiotensin AT1 receptor (CHO-AT1 cells). Coincubation with angiotensin AT1 receptor antagonists produced parallel rightward shifts of the concentration-response curve without affecting the maximal response.
Fierens, F L, Vanderheyden, P M, De Backer, J P, Vauquelin, G   +3 more
openaire   +3 more sources

Angiotensin Receptor Antagonists and Cardiovascular Remodeling

1998
Angiotensin (Ang) II is one of the key hormones involved in cardiovascular homeostasis. It has potent vasoconstrictor effects and is directly involved in the vascular and cardiac remodeling observed in response to chronic or acute hypertension. Two major Ang II receptor subtypes, AT1 and AT2, have been described, and their roles in vivo and in vitro ...
Sabri, K., Chassagne, Catherine, Lévy, B., Samuel, J.L., Rappaport, L.   +4 more
openaire   +1 more source

ACE Inhibitors and Angiotensin Receptor Antagonists and the Incidence of New-Onset Diabetes Mellitus

Drugs, 2012
D. Aguilar, S. Solomon
semanticscholar   +1 more source

Effect of Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Antagonists in Atherosclerosis Prevention

Current Cardiology Reports, 2012
Maria M. Patarroyo Aponte, G. Francis
semanticscholar   +1 more source

Systemic therapy for hormone receptor‐positive/human epidermal growth factor receptor 2‐negative early stage and metastatic breast cancer

Ca-A Cancer Journal for Clinicians, 2023
Laura A Huppert, Hope S Rugo
exaly  

A Systematic Comparison of the Properties of Clinically Used Angiotensin II Type 1 Receptor Antagonists

Pharmacological Reviews, 2013
M. C. Michel, C. Foster, H. Brunner, Li-sheng Liu   +3 more
semanticscholar   +1 more source

Chimeric antigen receptor T‐cell therapy in multiple myeloma: A comprehensive review of current data and implications for clinical practice

Ca-A Cancer Journal for Clinicians, 2023
Rujul Parikh
exaly