Results 231 to 240 of about 1,394,594 (296)

Medication Use and Risk of Microscopic Colitis: A Propensity‐Matched Analysis of US Adults ≥ 50 Years (2014–2024)

Alimentary Pharmacology &Therapeutics, EarlyView.
Commonly prescribed NSAIDs, PPIs and SSRIs were associated with a higher risk of microscopic colitis after propensity score matching, whereas ACE inhibitors, ARBs and statins showed no significant association. ABSTRACT Background The association between medications—including non‐steroidal anti‐inflammatory drugs (NSAIDs), proton pump inhibitors (PPIs ...
Yassine Kilani, Farah Heis, Andrew Dugaesescu, Youssef Hafez, Shadi Hamdeh, Wissam Kiwan, Mahmoud Y. Madi   +6 more
wiley   +1 more source

Prognostic effect of polypharmacy in ambulatory patients with heart failure: a machine learning-based analysis. [PDF]

BMC Cardiovasc Disord
Hooshanginezhad Z, Karvane HB, Mohammadi B, Nemati S.   +3 more
europepmc   +1 more source

The potential for biased signalling in the P2Y receptor family of GPCRs

British Journal of Pharmacology, EarlyView.
The purinergic receptor family is primarily activated by nucleotides, and contains members of both the G protein coupled‐receptor (GPCR) superfamily (P1 and P2Y) and ligand‐gated ion channels (P2X). The P2Y receptors are widely expressed in the human body, and given the ubiquitous nature of nucleotides, purinergic signalling is involved with a plethora
Claudia M. Sisk, Simon Pitchford, Graham Ladds   +2 more
wiley   +1 more source

G Protein-Coupled Receptor in High-Altitude Diseases: Mechanistic Insights and Therapeutic Opportunities. [PDF]

MedComm (2020)
Zhao Q, Liu C, Dai L, Zheng K, Liang K, Pan C, Liu L, Chen L, He X, Yan H, Chen L, Zheng H, Deng C, Luo F.   +13 more
europepmc   +1 more source

Renal‐vascular axis: unmasking its role in vascular endothelial growth factor‐inhibitor vascular toxicity in cancer patients

British Journal of Pharmacology, EarlyView.
Abstract Vascular toxicity is a growing concern in cancer patients receiving vascular endothelial growth factor inhibitor (VEGFi) therapy, posing a significant threat to patient prognosis. While the primary mechanism of VEGFi‐induced vascular toxicity is linked to redox‐sensitive reactions that disrupt vascular tone, leading to hypertension and ...
Grace Whelan, Karla B. Neves
wiley   +1 more source

Monogenic Kidney Disorders as Hidden Drivers of Electrolyte Imbalance and Hypertension. [PDF]

Electrolyte Blood Press
Ahn YH.
europepmc   +1 more source

Graded Associations Between Left Ventricular Ejection Fraction Improvement and Cardiorenal Outcomes in Heart Failure With Improved Ejection Fraction. [PDF]

J Am Heart Assoc
Lai CC, Huang SS, Lu YW, Wu CK, Wu YH, Tseng WC.   +5 more
europepmc   +1 more source

Hormonal Modulation in Chronic Coronary Syndrome: From Neurohormonal Activation to Endocrine Targets. [PDF]

Biomedicines
Brie AD, Popescu R, Mornoș C, Brie DM.
europepmc   +1 more source

Diuretics in Cardiovascular Disease: For How Long and at What Dose? [PDF]

J Cardiovasc Dev Dis
Paraskevaidis I, Tsougos E, Kourek C.
europepmc   +1 more source

Practical Implementation of Steroidal and Nonsteroidal Mineralocorticoid Receptor Antagonists in the Management of Heart Failure. [PDF]

JACC Adv
Michos ED, Ambrosy AP, Fonarow GC.
europepmc   +1 more source