Results 21 to 30 of about 86,631 (266)

Angiotensin receptor blockers and myocardial infarction [PDF]

BMJ, 2004
The interpretation of large scale clinical trials is being increasingly scrutinised by leading journals,1 with great emphasis being placed on the importance of sharing all potential side effects, no matter how trivial, with patients. The Lancet recently published the results of the valsartan antihypertensive long term use evaluation (VALUE) trial, a ...
Subodh, Verma, Marty, Strauss
openaire   +2 more sources

Angiotensin receptor blockers for bipolar disorder [PDF]

Medical Hypotheses, 2013
Studies have suggested that the brain renin angiotensin system (RAS) regulates cerebral flow, autonomic and hormonal systems, stress, innate immune response and behavior, being implicated in several brain disorders such as major depression, Parkinson's and Alzheimer's disease. The angiotensin II receptor subtype 1 (AT1R) is distributed in brain regions
Ana Isabelle, de Góis Queiroz, Camila Dantas, Medeiros, Bruna Mara Machado, Ribeiro, David Freitas, de Lucena, Danielle Silveira, Macêdo   +4 more
openaire   +2 more sources

Angiotensin receptor blocker neprilysin inhibitors

World Journal of Cardiology, 2021
Heart failure (HF) is a clinical syndrome that results from a structural or functional cardiac disorder that reduces the ability of the ventricle of the heart to fill with, or eject, blood. It is a multifaceted clinical condition that affects up to 2% of the population in the developed world, and is linked to significant morbidity and mortality; it is ...
Usuda, Daisuke, Higashikawa, Toshihiro, Hotchi, Yuta, Usami, Kenki, Shimozawa, Shintaro, Tokunaga, Shungo, Osugi, Ippei, Katou, Risa, Ito, Sakurako, Yoshizawa, Toshihiko, Asako, Suguru, Mishima, Kentaro, Kondo, Akihiko, Mizuno, Keiko, Takami, Hiroki, Komatsu, Takayuki, Oba, Jiro, Nomura, Tomohisa, Sugita, Manabu   +18 more
openaire   +2 more sources

Discontinuation of Heart Failure Pharmacotherapy in Older Adults With Frailty

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Guideline‐directed medical therapy (GDMT) improves outcomes in heart failure irrespective of frailty status. Nevertheless, the magnitude of frailty‐associated discontinuation of GDMT remains insufficiently studied.
Ryo Nakamaru, Shiori Nishimura, Hiraku Kumamaru, Kyohei Daigo, Kayo M. Walsh, Shun Kohsaka   +5 more
doaj   +1 more source

Intraoperative angioedema induced by angiotensin II receptor blocker: a case report

Patient Safety in Surgery, 2018
Background Angiotensin II receptor blockers are a class of antihypertensive agent that is developed to exclude the adverse effects of angiotensin converting enzyme inhibitors.
Ala”a Alhowary, Haitham Odat, Obada Alali, Ali Al-Omari   +3 more
doaj   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Acute Kidney Injury After Mechanical Thrombectomy for Stroke in Patients With Pre‐Existing Renal Impairment

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Acute kidney injury (AKI) is a common but often underrecognized complication in ischemic stroke patients undergoing mechanical thrombectomy, particularly among those with pre‐existing renal impairment. This study evaluated the incidence, risk factors, and clinical impact of AKI in this high‐risk population.
Michał Borończyk, Marcel Pilarek, Emilia Jaworska, Natalia Kardas, Oliwia Barnaś, Julia Woźniak, Iga Machała, Julia Węgrzynek‐Gallina, Joanna Siuda, Anna Hawrot‐Kawecka, Anetta Lasek‐Bal   +10 more
wiley   +1 more source

Renal implications of angiotensin receptor blockers [PDF]

American Journal of Hypertension, 2001
The role of the renin-angiotensin system (RAS) in the regulation of blood pressure and the pathogenesis of both hypertension and renal complications involves an intricate interplay of genetic and environmental factors. In the case of diabetic nephropathy, the genes governing the RAS are an obvious choice in the search for contributing factors.
openaire   +2 more sources

Angiotensin receptor blockers (ARBs) [PDF]

Canadian Medical Association Journal, 2011
Guertin and colleagues describe potential savings from restricting use of ARBs in Canada.[1][1] The US Department of Veterans Affairs prefers angiotensin-converting-enzyme (ACE) inhibitors over ARBs, with national criteria for use to guide prescribing.
W. F. Gellad, C. B. Good
openaire   +1 more source

Clinical, Histologic, and Serological Predictors of Renal Function Loss in Lupus Nephritis

Arthritis Care &Research, EarlyView.
Objective Kidney survival is the ultimate goal in lupus nephritis (LN) management, but long‐term predictors remain inadequately studied, requiring long‐term follow‐up. This study aimed to identify baseline and early longitudinal predictors of kidney survival in the Accelerating Medicines Partnership LN longitudinal cohort.
Shangzhu Zhang, Laurence Magder, Daniel Goldman, Judith A. James, Joel M. Guthridge, Carla Guthridge, Peter Izmirly, Jill P. Buyon, H. Michael Belmont, Richard A. Furie, Noa Schwartz, Chaim Putterman, Jennifer L. Barnas, Jennifer H. Anolik, Sarah French, Maria Dall'Era, Avi Z. Rosenberg, Jeffrey Hodgin, Dawit S. Demeke, the Accelerating Medicines Partnership Rheumatoid Arthritis and Systemic Lupus Erythematosus (RA/SLE) Network, Michelle Petri, Andrea Fava   +21 more
wiley   +1 more source