Results 51 to 60 of about 42,058 (273)

An Aerial Target Localization Method Using TOA and AOA Measurements with GEO-UAV Bistatic Configuration

Advances in Electrical and Computer Engineering
Based on multi-station spatial diversity capability, GEO-UAV distributed radar could achieve high-precision aerial target localization with the single-transmitting and multiple-receiving configuration. However, the actual observation area can hardly be
JIAO, X., ZHANG, J., CHEN, J., JIANG, L., WANG, Y., LI, Y., WANG, W.   +6 more
doaj   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

On the Security of Ultrasound as Out-of-band Channel [PDF]

, 2007
Ultrasound has been proposed as out-of-band channel for authentication of peer devices in wireless ad hoc networks. Ultrasound can implicitly contribute to secure communication based on inherent limitations in signal propagation, and can additionally be ...
Gellersen, Hans, Mayrhofer, Rene
core   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Robust spiked random matrices and a robust G-MUSIC estimator [PDF]

, 2014
A class of robust estimators of scatter applied to information-plus-impulsive noise samples is studied, where the sample information matrix is assumed of low rank; this generalizes the study of (Couillet et al., 2013b) to spiked random matrix models.
Couillet, Romain
core   +3 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Gaussian Channel Model for Mobile Multipath Environment

EURASIP Journal on Advances in Signal Processing, 2004
A model of an angle-spread source is described, termed the “Gaussian channel model” (GCM). This model is used to represent signals transmitted between a user equipment and a cellular base station.
D. D. N. Bevan, V. T. Ermolayev, A. G. Flaksman, I. M. Averin   +3 more
doaj   +1 more source

A new stochastic spatio-temporal propagation model (SSTPM) for mobile communications with antenna arrays [PDF]

, 2001
In order to evaluate the performance of third-generation mobile communication systems, radio channel models are required. The models should be capable of handling nonstationary scenarios with dynamic evolution of multipath. In this context and due to the
McGeehan, JP, Piechocki, RJ, Tsoulos, G
core   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Polynomial subspace decomposition for broadband angle of arrival estimation [PDF]

, 2014
In this paper we study the impact of polynomial or broadband subspace decompositions on any subsequent processing, which here uses the example of a broadband angle of arrival estimation technique using a recently proposed polynomial MUSIC (P-MUSIC ...
Alrmah, Mohamed Abubaker, Alzin, Ahmed, Corr, Jamie, Thompson, Keith, Weiss, Stephan   +4 more
core   +1 more source