NeuroImage: Clinical, 2023 Background: Several epidemiological studies and psychological models have suggested that major depressive disorder (MDD) with anhedonia is associated with suicidal ideation (SI).
Zhijian Yao, Yinghong Huang
exaly +3 more sources
The association of different dimensions of anhedonia in the relationship between depressive symptoms and self-harm in adolescents with mood disorders [PDF]
Frontiers in PsychiatryObjectiveAn increasing number of adolescents with mood disorders engage in self-harm. Anhedonia is independently associated with self-harm. Exploratory analyses in this cross-sectional study examined the associations of different dimensions of anhedonia ...
Jiping Xiao +23 more
doaj +2 more sources
Reward pursuit during a translational reward task correlates with anhedonia reductions following rTMS in patients with major depressive disorder [PDF]
Translational PsychiatryPeople with major depressive disorder (MDD) often struggle to pursue previously rewarding activities, which may relate to deficits experiencing pleasure, termed anhedonia. Anhedonia remains a challenge to target and treat.
Samantha V. Abram +5 more
doaj +2 more sources
Comparative multidimensional psychosocial profiles of major depressive disorder patients with higher versus lower anhedonia burden: a cross-sectional study [PDF]
BMC PsychiatryBackground Anhedonia is a core symptom of major depressive disorder (MDD) and is linked to greater severity, poorer functioning, and elevated suicide risk, yet its broader psychosocial correlates in routine clinical settings remain insufficiently ...
Ce Zhu +8 more
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Progress and challenges in research of the mechanisms of anhedonia in major depressive disorder
General Psychiatry, 2022 There is an increasing heavy disease burden of major depressive disorder (MDD) globally. Both high diagnostic heterogeneity and complicated pathological mechanisms of MDD pose significant challenges.
Yun-Ai Su, Tianmei Si
doaj +1 more source
Foods, 2022 Anhedonia, the diminished ability to experience pleasure, is a key symptom of a range of mental and neurobiological disorders and is associated with altered eating behavior.
Nikoline Bach Hyldelund +3 more
doaj +1 more source
Phenotypic and genetic associations between anhedonia and brain structure in UK Biobank
Translational Psychiatry, 2021 Anhedonia is a core symptom of multiple psychiatric disorders and has been associated with alterations in brain structure. Genome-wide association studies suggest that anhedonia is heritable, with a polygenic architecture, but few studies have explored ...
Xingxing Zhu +6 more
doaj +1 more source
Suicidal Ideations in Major Depressed Subjects: Role of the Temporal Dynamics of Anhedonia
Brain Sciences, 2023 Given the limited data available in the literature, the aim of this study was to investigate the potential role played by the temporal dynamics of anhedonia (lifelong anhedonia and recent changes in anhedonia) in the occurrence of suicidal ideations in ...
Gil Darquennes +3 more
doaj +1 more source
Brain and Behavior, 2021 Background Anhedonia is one of the defining features of depression but it remains difficult to target and treat. Transcranial magnetic stimulation (TMS) is a proven treatment for depression, but its effects on anhedonia and whether anhedonia can be used ...
Andrew M. Fukuda +5 more
doaj +1 more source
Struggling toward reward: Recent experience of anhedonia interacts with motivation to predict reward pursuit in the face of a stressful manipulation. [PDF]
PLoS ONE, 2017 Anhedonia, or the loss of interest and/or pleasure, is a core symptom of depression. Individuals experiencing anhedonia have difficulty motivating themselves to pursue rewarding stimuli, which can result in dysfunction.
Jessica Bryant +3 more
doaj +1 more source