Results 31 to 40 of about 7,998 (258)

Anhedonia in cocaine use disorder is associated with inflammatory gene expression. [PDF]

PLoS ONE, 2018
Treatments for Cocaine Use Disorder (CUD) are variably effective, and there are no FDA-approved medications. One approach to developing new treatments for CUD may be to investigate and target poor prognostic signs. One such sign is anhedonia (i.e. a loss
Gabriel Rodrigo Fries, Sarwar Khan, Sydney Stamatovich, Elena Dyukova, Consuelo Walss-Bass, Scott D Lane, Joy M Schmitz, Margaret C Wardle   +7 more
doaj   +1 more source

Temperament and character inventory dimensions and anhedonia in detoxified substance-dependent subjects

, 2008
In this study we aimed to investigate the relationship between anhedonia, craving and temperament and character dimensions in a sample of 50 patients with alcohol and opiate dependence recruited after a period of detoxification. The following scales were
Martinotti, Giovanni, Janiri, Luigi
core   +1 more source

The effect of physical activity on anhedonia in individuals with depressive symptoms

, 2021
The therapeutic effect of antidepressants has been demonstrated for anhedonia in patients with depression. However, antidepressants may cause side-effects, such as cardiovascular dysfunction.
Shum, David H. K., Yu‐qi Fang, Fang, Yu-qi, So, Billy CL, Wang, Xuan, Wang, Ya-jing, Shum, David HK, Yan, Chao, Ya‐jing Wang, Yu‐qian He, He, Yu-qian, Chao Yan, Xuan Wang, Sun, Ching-wen, So, Billy C. L., David H. K. Shum, Billy C. L. So, Ching‐wen Sun   +17 more
core   +1 more source

The association of different dimensions of anhedonia in the relationship between depressive symptoms and self-harm in adolescents with mood disorders

Frontiers in Psychiatry
ObjectiveAn increasing number of adolescents with mood disorders engage in self-harm. Anhedonia is independently associated with self-harm. Exploratory analyses in this cross-sectional study examined the associations of different dimensions of anhedonia ...
Jiping Xiao, Jiping Xiao, Jiping Xiao, Dandan Liu, Dandan Liu, Dandan Liu, Li Cheng, Li Cheng, Li Cheng, Mian Zhang, Mian Zhang, Mian Zhang, Ming Wu, Ming Wu, Ming Wu, Nan Du, Nan Du, Nan Du, Li Zhu, Li Zhu, Li Zhu, Daomin Zhu, Daomin Zhu, Daomin Zhu   +23 more
doaj   +1 more source

Anticipatory and Consummatory Anhedonia in Individuals with Schizotypal Traits

, 2014
Anhedonia is the reduced ability to experience pleasure emotion and has been considered a key symptom in schizophrenia spectrum disorders. However, little is known about the hedonic capacity and related neural basis for individuals prone to develop ...
Yi Wang, Wang, Yi, Chao Yan, Simon S. Y. Lui, Chan, Raymond C.K., Qi-feng Yin, Eric F. C. Cheung, Cheung, Eric F.C., Yin, Qi Feng, Lui, Simon S.Y., Raymond C. K. Chan, Yan, Chao   +11 more
core   +1 more source

Personalized Network‐Guided Neuromodulation Enhances Human Working Memory

Advanced Science, EarlyView.
A personalized neuromodulation framework combining individualized functional brain network targeting with real‐time neural decoding is introduced. Using concurrent TMS–fMRI, participant‐specific stimulation targets and optimal frequencies are identified. Only optimal‐frequency stimulation improves working memory across sessions.
Ahsan Khan, Hongming Li, Camille Blaine, Julie Grier, Ethan Hammett, Almaris Figueroa‐Gonzalez, Sarai Garcia, Romain Duprat, Justin Reber, Joseph Deluisi, Christos Davatzikos, Theodore D. Satterthwaite, Yong Fan, Desmond J. Oathes   +13 more
wiley   +1 more source

Association of Cognitive Impairment With Anhedonia in Patients With Schizophrenia

Frontiers in Psychiatry, 2021
Anhedonia is considered as one of the five dimensions of negative symptoms and mainly refers to the reduction of the capacity of feeling pleasure.
Lingfang Yu, Hua Ni, Zenan Wu, Xinyu Fang, Yan Chen, Dandan Wang, Chen Zhang   +6 more
doaj   +1 more source

Astrocytic Phenotypic Switching in Posterior Piriform Cortex Orchestrates Bone Cancer Pain–Depression Comorbidity via Purinergic–Noradrenergic Signaling

Advanced Science, EarlyView.
Bone cancer pain and depression share a common origin: astrocytic A2‐to‐A1 transition in the posterior piriform cortex. This phenotypic shift disrupts the ATP–adenosine–A2AR–norepinephrine axis, simultaneously driving nociceptive and affective dysfunction.
Jiang‐Ping Liu, Jun‐Han Zhang, Zhi‐Xuan Tan, Wei‐Bing Yan, Ya‐Ru Yuan, Yao Liu, Bing‐Di Wei, Meng‐Qi Ding, Zhuo‐Min Fu, Ying Liu, An‐Qi Wang, Lin Ma, Yong‐Hong Li, Er‐Qing Chai, Chao‐Jun Wei   +14 more
wiley   +1 more source

Effects of olanzapine on anhedonia in schizophrenia: mediated by complement factor H

Frontiers in Psychiatry, 2023
BackgroundAnhedonia is a trans-diagnostic symptom in schizophrenia and MDD. Our recent work indicated that increased plasma level of complement factor H (CFH) is associated with anhedonia in major depressive disorder.
Yi Zhang, Wei Tang, Weiping Wang, Feikang Xu, Weihong Lu, Chen Zhang, Chen Zhang   +6 more
doaj   +1 more source

Motivation deficits in individuals with social anhedonia

, 2018
Patients with schizophrenia have been reported to exhibit anhedonia, a reduced hedonic capacity and deficits in motivation for reward pursuit. However, it is unclear whether these deficits also exist in at-risk individuals prone to psychosis or not.
Yue, Xiao dong, Jiao Wang, Chan, Raymond C. K., Chan, RCK, Cheung, EFC, Wang, Jiao, Jia Huang, Raymond C.K. Chan, Chan, Raymond C.K., Cheung, Eric F.C., J. Huang, Huang, Jia, Wang, J, Xiao-dong Yue, Yue, Xiao-dong, Cheung, Eric F. C., Huang, J, Simon S.Y. Lui, Yue, XD, Lui, Simon S. Y., Lui, SSY, Lui, Simon S.Y., Eric F.C. Cheung   +22 more
core   +1 more source