Results 31 to 40 of about 45,951 (270)

Anhedonia in postpartum rats [PDF]

open access: yesPhysiology & Behavior, 2010
Postpartum depression (PPD) is a debilitating illness, yet little is known about its causes. The purpose of this study was to examine a major symptom of depression during the postpartum period, anhedonia, by comparing sucrose preference in female rats that had undergone actual pregnancy or hormone-simulated pregnancy (HSP) to their respective controls.
NAVARRE, Brittany M   +2 more
openaire   +3 more sources

Analysis of the component factors and connected factors of anhedonia in patients with first-episode schizophrenia

open access: yesSichuan jingshen weisheng, 2021
ObjectiveTo explore the component factors of anhedonia in first-episode schizophrenia patients and the relationship with clinical symptoms, cognitive and social functioning.MethodsA total of 31 patients with first-episode schizophrenia who met the ...
Li Haijing   +4 more
doaj   +1 more source

Insulin Resistance, Temperament and Personality Traits Are Associated with Anhedonia in a Transdiagnostic Sample

open access: yesBrain Sciences
Anhedonia constitutes a core symptom of major depressive disorder (MDD) mediating the ultimate goal of MDD treatment: functional remission. Anhedonia is also present in other clinical populations, including patients with chronic pain.
Marcin Siwek   +4 more
doaj   +1 more source

Temperament and character inventory dimensions and anhedonia in detoxified substance-dependent subjects

open access: yes, 2008
In this study we aimed to investigate the relationship between anhedonia, craving and temperament and character dimensions in a sample of 50 patients with alcohol and opiate dependence recruited after a period of detoxification. The following scales were
Martinotti, Giovanni, Janiri, Luigi
core   +1 more source

Anhedonia w zaburzeniach depresyjnych [PDF]

open access: yes, 2017
Anhedonia bywa elementem obrazu klinicznego wielu zaburzeń psychicznych i neurologicznych, jednak najczęściej i w sposób najbardziej typowy występuje w przebiegu epizodu depresyjnego, jako jeden z jego osiowych objawów.
Siwek, Marcin, Marcin Siwek
core   +2 more sources

Anhedonia in the shadow of chronic social defeat stress, or When the experimental context matters [PDF]

open access: yes, 2008
One of the core symptoms of major depression in human is anhedonia. For that reason, one of the main requirements towards experimental depression models is that they be able to demonstrate anhedonia in animals, that have been exposed to stressful events,
Dmitry A. Smagin   +4 more
core  

Anticipatory and Consummatory Anhedonia in Individuals with Schizotypal Traits

open access: yes, 2014
Anhedonia is the reduced ability to experience pleasure emotion and has been considered a key symptom in schizophrenia spectrum disorders. However, little is known about the hedonic capacity and related neural basis for individuals prone to develop ...
Yi Wang   +11 more
core   +1 more source

Disrupted TFEB/GDNF–cAMP/ATP Coupling Underlies Astrocytic Dysfunction and Depression in LRRK2 G2019S Parkinson's Mice

open access: yesAdvanced Science, EarlyView.
ABSTRACT The LRRK2 G2019S mutation, a Parkinson's disease–linked variant, has been associated with depression‐like phenotypes, but mechanisms remain unclear. We chart age‐dependent behavioral changes and astrocyte reactivity in G2019S mice and define a pathway connecting LRRK2 to TFEB/GDNF signaling, cellular energetics, and inflammation.
Longping Yao   +5 more
wiley   +1 more source

Sociomarkers of anhedonia in MDD [PDF]

open access: yes, 2019
Background: Anhedonia is one of the two core symptoms of MDD, described as the decreased ability to experience pleasure in daily life. We aimed to describe anhedonia in everyday life of patients with Major Depressive Disorder (MDD), and investigate its ...
Heininga, Vera E.   +4 more
core   +2 more sources

Anhedonia in cocaine use disorder is associated with inflammatory gene expression. [PDF]

open access: yesPLoS ONE, 2018
Treatments for Cocaine Use Disorder (CUD) are variably effective, and there are no FDA-approved medications. One approach to developing new treatments for CUD may be to investigate and target poor prognostic signs. One such sign is anhedonia (i.e. a loss
Gabriel Rodrigo Fries   +7 more
doaj   +1 more source

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