Results 131 to 140 of about 7,998 (258)

The association between attachment insecurity and negative symptoms in clinical and non‐clinical populations: A systematic review and meta‐analysis

Psychology and Psychotherapy: Theory, Research and Practice, EarlyView.
Abstract Purpose Attachment insecurity has been theorised to be associated with the development and maintenance of negative symptoms. Previous reviews examining the relationship between attachment insecurity and negative symptoms of psychosis have produced conflicting findings.
Aiden Duffy, David Carmichael, Zsofia K. Takacs, Regina Murphy, Sean Harper, Tia McEwan, Karen Goodall   +6 more
wiley   +1 more source

Immune dysregulation in mania: A proof‐of‐concept platelet proteomics study

Psychiatry and Clinical Neurosciences, EarlyView.
Aims Bipolar disorder (BD) is a major psychiatric condition with a multifaceted and largely unknown pathophysiology. Mania, the defining feature of BD, remains underinvestigated. Proteomics offers a powerful, data‐driven, unbiased approach to uncover biological alterations.
Paola Magioncalda, Matteo Martino, Nhi Thao Ngoc Le, Wen‐Yin Chen, Ming‐Chyi Huang, David Blum, Thierry Burnouf   +6 more
wiley   +1 more source

Reward Motivation Adaptation Deficits Are Specific to Co-Occurring Subclinical Depression and Anhedonia

Behavioral Sciences
Reward motivation adaptation is defined as the extent to which the willingness to exert effort varies as a function of incentive salience, encompassing both motivational (‘wanting’) and hedonic (‘liking’) components.
Xin Gao, Jie Pu, Xinyue Zhao, Yuxi Zhao, Wenting Mu, Simon S. Y. Lui, Jia Huang, Raymond C. K. Chan   +7 more
doaj   +1 more source

ANHEDONIA IN SCHIZOPHRENIA: MINI-REVIEW

, 2019
The perception of reward exerts a powerful influence on human behavior. While anhedonia might occur in healthy individuals, its prevalence and severity are much higher in psychiatric patients, particularly those with depression and schizophrenia ...
Tudor, Lucija, Jakšić, Nenad Jakšić, Kosanović Rajačić, Biljana, Pivac, Nela, Madžarac, Zoran, Šimunić, Lucija Šimunić, Kudlek Mikulić, Suzan, Šagud, Marina, Vuksan-Ćusa, Bjanka, Stefanović, Ivana, Šimunović Filipčić, Ivona, Mihaljević Peleš, Alma, Jezernik, Dejana   +12 more
core  

Biological Mechanisms Linking Stress and Anhedonia

, 2021
Evidence from research across species suggests that stress exposure is linked with anhedonia (loss of pleasure and/or decreased motivation). However, the mechanisms through which stress might impact anhedonia remain unclear.
Stanton, Colin
core  

Integrative methylation and miRNA dysregulation in dlPFC reveal distinct molecular signatures of suicide and non‐suicide subtypes in major depressive disorder

Psychiatry and Clinical Neurosciences, EarlyView.
Aim Major depressive disorder (MDD) is a leading cause of disability and carries a high risk of suicide. MicroRNAs (miRNAs) are epigenetic regulators implicated in MDD and can be regulated by DNA methylation, potentially reshaping downstream gene networks.
Aleena Francis, Yogesh Dwivedi
wiley   +1 more source

Characterizing social motivation deficits in treatment‐resistant schizophrenia: Evidence from social incentive performance

Psychiatry and Clinical Neurosciences, EarlyView.
Aim The Treatment‐Response‐and‐Resistance‐in‐Psychosis (TRRIP) criteria recognizes negative symptoms as defining features for treatment‐resistant schizophrenia (TRS). Social motivation refers to the desire to pursue social reward (and to avoid social punishment).
Simon S.Y. Lui, Jasmine W.S. Chan, Jason L.F. Chan, Kimi H.Y. Lam, Lok‐Yin Choi, Raisie W.K. Wong, Perry B.M. Leung, Na Zhan, Jason W.Y. Wong, Mindi W.Y. Chiu, Jenny P.H. Lam, Raymond C.K. Chan   +11 more
wiley   +1 more source

The specific mediating role of social anhedonia in the relationship between childhood emotional abuse and depressive symptoms in bipolar disorder

BMC Psychiatry
Background Childhood trauma is a well-established risk factor for greater severity and poorer prognosis of bipolar depression. While anhedonia particularly in the social domain is theorized to link early adversity to depressive symptoms, this specific ...
Peiyun Zhang, Qianqian Qin, Kaihong Tang, Weihong Jiang, Chao Liu, Qi Yan   +5 more
doaj   +1 more source

The neural basis of olfactory function and its relationship with anhedonia in individuals with schizotypy: An exploratory study

, 2015
Previous studies have established a linkage between olfactory deficits and negative symptoms in schizophrenia. However, it is not known whether olfactory function is associated with hedonic traits in individuals with schizotypy.
Wang, Yi, Wei, Xin-hua, Chan, Raymond C. K., Liu, Wen-hua, Shi, Hai-song, Zou, Lai-quan, Geng, Fu-lei, Cheung, Eric F. C., Jiang, Xin-qing, Lui, Simon S. Y.   +9 more
core  

Associations Between Facets of Pathological Personality Traits and Alexithymia: The Roles of Detachment and Negative Affect

Scandinavian Journal of Psychology, EarlyView.
ABSTRACT The current study examined (1) whether underlying facets of Detachment and Negative Affect are associated with the different components of alexithymia, and (2) whether these associations depend on the level of perceived stress. In total, 635 students (Mage = 20.02, 87.5% female) filled out online questionnaires on alexithymia (Toronto ...
Stefanie Duijndam, Rosie Kidane, Paul Lodder, Nathan Bachrach   +3 more
wiley   +1 more source