Results 181 to 190 of about 7,998 (258)

Lanzhou Lily (Lilium davidii var. unicolor) Extract Alleviates Chronic Stress–Induced Mood Disturbances by Suppressing Neuroinflammation and Modulating the Gut‐Brain Axis in Mice

open access: yesFood Science &Nutrition, Volume 14, Issue 6, June 2026.
Lanzhou lily extract (LLE) alleviates chronic restraint stress–induced mood disturbances by reducing central inflammation, improving intestinal barrier integrity, attenuating systemic inflammation, and ultimately restoring gut–brain axis homeostasis in mice.
Ziyi An   +7 more
wiley   +1 more source

Dysregulation of the TLR4/MyD88/NF‐κB Signaling Pathway and Pro‐Inflammatory Cytokines in First‐Episode Major Depressive Disorder: A Cross‐Sectional Case–Control Study

open access: yesImmunity, Inflammation and Disease, Volume 14, Issue 6, June 2026.
ABSTRACT Introduction Inflammation is increasingly recognized as a key contributor to the development and progression of major depressive disorder (MDD). This case–control study aims to assess the expression of inflammatory pathway components (TRIF, MyD88, NF‐κB) and serum levels of TNF‐α and IL‐6 in remitted and untreated MDD patients compared to ...
Yaser Mohammadi   +4 more
wiley   +1 more source

Dark Triad Traits Affect the Perception of Emotions in Animal Calls

open access: yesInternational Journal of Psychology, Volume 61, Issue 3, June 2026.
ABSTRACT Humans can recognize emotions from vocalisations of various animal species. Our study examined whether human psychological differences in dark personality traits (as measured by SD3) and musician experience affect the decoding of emotions in animal calls.
Iva Linda Maruščáková   +3 more
wiley   +1 more source

Evaluating Brief Behavioural Activation for depression in adolescents with acquired brain injury using a single‐case experimental design

open access: yesJCPP Advances, Volume 6, Issue 2, June 2026.
Abstract Background Adolescents who have had an acquired brain injury (ABI) commonly experience depression. Brief Behavioural Activation (Brief BA) is a successful, values‐based intervention for managing depression in neurotypical adolescents. This study investigated the effectiveness of Brief BA, using a single‐case experimental design, with ...
Conor R. O’Brien   +4 more
wiley   +1 more source

When the Scale Drops: Pathways to Weight Loss in Parkinson's Disease and Future Directions

open access: yesMovement Disorders, Volume 41, Issue 6, Page 1337-1348, June 2026.
Abstract Although Parkinson's disease (PD) is classically defined by its motor features, non‐motor symptoms exert a substantial and often under‐recognized influence on disease trajectory. Among these, weight loss has long been observed in PD and other neurodegenerative disorders, yet the mechanisms remain incompletely understood.
Ellie D. Gabriel   +6 more
wiley   +1 more source

Perspective: Depression in Persons with Parkinson's Disease

open access: yesMovement Disorders, Volume 41, Issue 6, Page 1355-1361, June 2026.
Abstract Depression is a prevalent and disabling syndrome characterized by sustained sadness and/or anhedonia, as well as cognitive and physical symptoms. In Parkinson's disease (PD), depression is both common and clinically challenging due to overlapping symptoms and complex etiologic interactions. Major depressive disorder occurs in approximately 17%
Albert F.G. Leentjens   +1 more
wiley   +1 more source

Psychometric Validity of the CES‐D Scale for Assessing Depressive Symptoms in University Students in Bogotá. Colombia

open access: yesInternational Journal of Methods in Psychiatric Research, Volume 35, Issue 2, June 2026.
ABSTRACT Introduction The Center for Epidemiological Studies Depression Scale (CES‐D) is a widely used tool for assessing depressive symptoms. This study examined its psychometric properties in a sample of 1738 university students in Bogotá. Methods Instrumental study with a cross‐sectional, single‐center design with two‐stage sampling. Exploratory and
Angela Gissette Caro‐Delgado   +3 more
wiley   +1 more source

Building a Brief Multidomain Questionnaire for Gambling Dual Disorder: Psychometric Validation and RDoC‐Based Dimensional Structure

open access: yesInternational Journal of Methods in Psychiatric Research, Volume 35, Issue 2, June 2026.
ABSTRACT Objectives Gambling Disorder (GD) frequently co‐occurs with other mental disorders, a clinical condition termed Gambling Dual Disorder (GDD) that is often overlooked. We aimed to develop and validate a brief multidomain questionnaire to assess GDD severity within a dimensional, transdiagnostic framework.
Ignacio Basurte‐Villamor   +6 more
wiley   +1 more source

The Latent Structure of Depression and Anxiety Symptoms: A Bifactor Exploratory Structural Equation Model of the PHQ‐9 and GAD‐7 in Primary Care

open access: yesInternational Journal of Methods in Psychiatric Research, Volume 35, Issue 2, June 2026.
ABSTRACT Introduction The high comorbidity between depression and anxiety challenges traditional nosological models. In order to better reflect this overlap, dimensional approaches seek to clarify whether these symptoms reflect a single underlying construct of general distress or a more complex multidimensionality. The aim was to examine the underlying
Gabriel Esteller‐Collado   +9 more
wiley   +1 more source

Psychometric Validation of the PHQ‐9 in Ostomy Patients and Their Informal Caregivers: Evidence From A European Multicenter Study

open access: yesNursing Open, Volume 13, Issue 6, June 2026.
ABSTRACT Introduction Depressive symptoms are highly prevalent among individuals with an ostomy and their informal caregivers, negatively affecting quality of life and healthcare outcomes. Although the Patient Health Questionnaire‐9 (PHQ‐9) is widely used for depression screening, its psychometric properties have not previously been examined ...
Paolo Iovino   +4 more
wiley   +1 more source

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