Results 81 to 90 of about 381,835 (335)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Farmer Consumer Partnerships: Information search and decision making - the case of ethical values of organic products [PDF]

, 2009
The CORE Organic pilot project ‘Farmer Consumer Partnerships’ aims at analysing and testing innovative communication strategies of organic companies with respect to ethical values as a means of reconnecting organic farmers and consumers against the ...
Hamm, Ulrich, Zander, Katrin
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Patient benefit of dog-assisted interventions in health care: a systematic review

BMC Complementary and Alternative Medicine, 2017
Background Dogs are the most common companion animal, and therefore not surprisingly a popular choice for animal-assisted interventions. Dog-assisted interventions are increasingly used in healthcare.
Martina Lundqvist, Per Carlsson, Rune Sjödahl, Elvar Theodorsson, Lars-Åke Levin   +4 more
doaj   +1 more source

Healing dolphins? Cognitive and perceptual criticisms in Dolphin-Assisted Therapy [PDF]

, 2015
Since the '70s new therapeutic practices have been developed, involving the interaction between humans and dolphins - Tursiops truncatus in particular. Such practices are known as Dolphin-Assisted Therapies (DAT), a specific case of a more heterogeneous ...
Candelieri, Irene, Cattaruzza, Serena, Chiandetti, Cinzia   +2 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Animal-assisted and nature-based intervention on a farm for young adults with autism and social withdrawal – A one-year follow-up with a socioeconomic approach

Scandinavian Journal of Occupational Therapy
Background Interventions in the form of animal-assisted and nature-based activities are promising for young adults with autism, but there is a knowledge gap concerning the long-term values of these.Aim The aim was to describe the activity levels in daily
Sara Holmberg, A. Birgitta Gunnarsson
doaj   +1 more source

Dog Training Intervention Shows Social-Cognitive Change in the Journals of Incarcerated Youth

Frontiers in Veterinary Science, 2018
There is limited research assessing the effectiveness of Animal-Assisted Therapy in at-risk adolescent populations. In a recent study, 138 adjudicated adolescents participated in a randomized controlled trial of an animal-assisted intervention, in which ...
Tiffany Syzmanski, Rita J. Casey, Amy Johnson, Annmarie Cano, Dana Albright, Nicholas P. Seivert   +5 more
doaj   +1 more source