Results 51 to 60 of about 92,372 (289)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Animal-assisted interventions in mainstream schools: What works? [PDF]

open access: yes, 2019
The inclusion of animals within the educational environment has increased in popularity in recent years, with many positive aspects being credited to the practice (Gee, Fine, McCardle, 2017; Fine, 2015). Whilst the value of animal-assisted interventions (
Victoria Brelsford (17154487)
core   +1 more source

A One Health Research Framework for Animal-Assisted Interventions [PDF]

open access: yesInternational Journal of Environmental Research and Public Health, 2019
Background: The integration of animals into healthcare, referred to as animal-assisted intervention, is a rapidly growing research field and was previously related to One Health. However, the assessment of synergistic effects of animal-assisted interventions (AAI) has been poorly addressed to date. Method: We discuss experiences in integrated human and
Karin Hediger   +2 more
openaire   +4 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Animal-assisted intervention and social skills strengthening [PDF]

open access: yes, 2014
The diploma thesis describe animal-assisted interventions, more precisely, the significance of animal-assisted interventions for strengthening of social skills.
Božič, Tjaša
core  

Development of a Animal Assisted Therapy Intervention Manual and Screening Tool for the Pediatric Population [PDF]

open access: yes, 2022
The doctoral capstone project aims to 1) create a pediatric animal assisted therapy intervention manual and 2) screening tool to promote appropriate and diverse usage of AAT for increased goal achievement.
O\u27Keefe, Moira
core  

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

A comparison of equine-assisted intervention and conventional play-based early intervention for mother-child dyads with insecure attachment [PDF]

open access: yes, 2015
Early interventions aim at promoting a good mother–child relationship as basis for a good socio-emotional development, especially in high-risk populations, and at correcting already unfavorable patterns of interaction and are common today.
Uvnäs-Moberg, Kerstin,   +1 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

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