Results 61 to 70 of about 4,395,835 (285)
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Animal-assisted intervention and social skills strengthening [PDF]
, 2014 The diploma thesis describe animal-assisted interventions, more precisely, the significance of animal-assisted interventions for strengthening of social skills.
Božič, Tjaša
core
The Use of Animal-Assisted Therapy in Educational Settings
, 2023 Animal-Assisted therapy is a form of goal-based intervention where an animal is a part of the treatment process. This study evaluated two different interventions that use animal-assisted therapy practices in educational settings.
Morris, Jasmine
core +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
, 2022 The doctoral capstone project aims to 1) create a pediatric animal assisted therapy intervention manual and 2) screening tool to promote appropriate and diverse usage of AAT for increased goal achievement.
O\u27Keefe, Moira
core
Scientific Reports, 2022 Transdiagnostic psychotherapeutic approaches are increasingly used in neurorehabilitation to address psychological distress. Animal-assistance is thought to increase efficacy.
Pascale Künzi +4 more
doaj +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
An Animal-Assisted Intervention in an Australian University
, 2023 This thesis involved three phases. The first reviewed existing studies and illustrated an Animal Assisted Intervention (AAI) could improve stress, anxiety or mood on-campus. The second determined considerations required to implement an AAI.
Emily Cooke (15419141)
core
Social SciencesThis qualitative study explores the perceptions of mothers who are victims of domestic violence regarding their children’s interactions during animal-assisted activities conducted over three months in a residential shelter.
Inês da Silva Santos, Ana Isabel Sani
doaj +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source