Results 81 to 90 of about 597,981 (301)

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Contribution to the feeding ecology of the banded puffer fish Colomesus psittacus (Tetraodontidae) in north Brazilian mangrove creeks

open access: yesBrazilian Journal of Biology
Stomach contents were examined from 102 banded puffer, Colomesus psittacus (Tetraodontidae), caught from intertidal mangrove creeks at diurnal neap tides between June and September, 1997 (early dry season) near Bragança (north Brazil).
U. Krumme   +3 more
doaj   +1 more source

Arkansas Animal Science Department Report 2002 [PDF]

open access: yes, 2002
The faculty and staff of the Animal Science Program are pleased to present the sixth edition of the Arkansas Animal Science Report. As with virtually all programs in the country, budget constraints presented serious challenges to teaching, research, and ...
Johnson, Zelpha B., Kellogg, D. Wayne
core   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

THE INSTITUTIONAL PROBLEMS OF FINANCIAL AGRICULTURAL SUPPORT

open access: yesВестник Северо-Кавказского федерального университета, 2022
The interaction between the authority and economic structures demands using the institutes of financial agricultural support. In this case the growth of plant and animal production depends on financing farmers volumes establishing by WTO rules.
Sergey M. Gorlov
doaj  

Frugivory and Seed Dispersal by Lizards: A Global Review

open access: yesFrontiers in Ecology and Evolution, 2019
Birds and mammals are the only vertebrates which receive comprehensive attention in studies of dispersal of fleshy-fruited plant species. However, recently the importance of fleshy fruit in the diet of lizards (order Squamata: suborder Sauria), and their
Alfredo Valido, Jens M. Olesen
doaj   +1 more source

Functional characterization of two plant type I MADS-box genes in Arabidopsis thaliana : AGL40 and AGL62 : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Plant Biology at Massey University, Palmerston North, New Zealand [PDF]

open access: yes, 2008
MADS-box transcription factors (TF) are a family of evolutionary conserved genes found across various eukaryotic species. Characterized by the conserved DNA binding MADS-box domain.
Kaji, Ryohei
core  

LRR-containing receptors regulating plant development and defense [PDF]

open access: yes, 2004
Despite the presence of more than 400 genes that encode receptor-like kinases (RLKs) in the Arabidopsis thaliana genome, very little is known about the range of biological processes that they control, or the mechanisms by which they function. This review
Clark, Steven E., Dievart, Anne
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Home - About - Disclaimer - Privacy