Results 91 to 100 of about 597,981 (301)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Plant-based dietary orientation and body composition: a cross-sectional study

Discover Food
Background The growing need for a sustainable and personalised diet requires new tools to evaluate plant-based dietary orientation. Methods We developed a composite dietary score combining food preferences and weekly consumption frequency to quantify ...
Mauro Lombardo
doaj   +1 more source

Fungal entomopathogens: new insights on their ecology [PDF]

, 2009
An important mechanism for insect pest control should be the use of fungal entomopathogens. Even though these organisms have been studied for more than 100 y, their effective use in the field remains elusive.
Andrews, Arnold, Arnold, Arnold, Arnulfo Monzón, Askary, Audoin, Bardgett, Bark, Baverstock, Benhamou, Benhamou, Blackwell, Blackwell, Bonnie H. Ownley, Bourne, Bruck, Chamberlain, Cooke, Cory, Currie, David Chandler, De Leij, Dicke, Drauzio E.N. Rangel, Dunlap, Elliot, Faria, Fernando E. Vega, Gaugler, Goettel, Gottwald, Greif, Griffin, Groden, Gurr, Gurr, Helen E. Roy, Hibbett, Holder, Hu, Humber, Hywel-Jones, Inglis, Jaronski, Jones, Judith K. Pell, Kabaluk, Kerry, Kim, Kim, Kirk, Koske, Krassilstschik, Langewald, LeConte, Lee, Lewis, Little, Luangsa-ard, Mark A. Jackson, Mark S. Goettel, Masanori Koike, Meredith Blackwell, Meyling, Meyling, Nguya K. Maniania, Nikoh, Oerke, Ormond, Ownley, Ownley, Ownley, Ownley, Pasteur, Pereira, Rangel, Reisenzein, Renwick, Roberts, Roberts, Roy, Rudgers, Sabelis, Saikkonen, Schulz, Siegfried Keller, Singh, Spatafora, St. Leger, St. Leger, Staples, Strasser, Sung, Tanada, Taylor, Thacker, van Dam, Vega, Vega, Vesely, Waage, Welsh, Whipps, Wraight   +104 more
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

THE ECOLOGY OF MUTUALISM [PDF]

, 1982
Elementary ecology texts tell us that organisms interact in three fundamen­ tal ways, generally given the names competition, predation, and mutualism. The third member has gotten short shrift (264), and even its name is not generally agreed on.
Boucher, Douglas H., James, Sam, Keeler, Kathleen H.   +2 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

A novel role for the TIR domain in association with pathogen-derived elicitors [PDF]

, 2007
Plant innate immunity is mediated by Resistance (R) proteins, which bear a striking resemblance to animal molecules of similar function. Tobacco N is a TIR-NB-LRR R gene that confers resistance to Tobacco mosaic virus, specifically the p50 helicase ...
Burch-Smith, TM, Caplan, JL, Czymmek, K, Dinesh-Kumar, SP, Schiff, M, Tsao, J   +5 more
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source