A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
Animal suicide: An account worth giving? Commentary on Peña-Guzmán on Animal Suicide [PDF]
Peña-Guzmán (2017) argues that empirical evidence and evolutionary theory compel us to treat the phenomenon of suicide as continuous in the animal kingdom.
Mikhalevich, Irina
core
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Why Animal Law Matters: Establishing Animal Law Section in Era of Emerging Issues [PDF]
This article defines animal law and discusses some of the areas of practice that deal with animal law ...
Huss, Rebecca J.
core +1 more source
How can veterinarians be interesting partners for organic dairy farmers? French farmers’ point of views [PDF]
Organic dairy farmers must live up to the organic goal of ‘good health’ in respect the organic principles and regulation. Veterinarians could be the organic dairy farmers’ expected sparring partners in reaching this goal but have found difficulties to ...
Bareille, Nathalie +4 more
core +3 more sources
Hematopoietic (stem) cells—The elixir of life?
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
The experience of animal therapy in residential aged care in New Zealand : a narrative analysis : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Psychology at Massey University, Wellington, New Zealand [PDF]
Volunteer-led animal visitation programmes are common within Aged Residential Care facilities in New Zealand. Visits by animals and handlers, often referred to as Animal Therapy, are primarily social and intended to improve the quality of life of ...
Wong, Gemma Pui Yee
core
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley +1 more source
Cooperation in manure-based biogas production networks: An agent-based modeling approach [PDF]
Biogas production from manure has been proposed as a partial solution to energy and environmental concerns. However, manure markets face distortions caused by considerable unbalance between supply and demand and environmental regulations imposed for soil
Fraccascia, Luca +3 more
core +4 more sources

