Results 121 to 130 of about 882,472 (267)

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Vancomycin‐Induced Kidney Injury: Animal Models of Toxicodynamics, Mechanisms of Injury, Human Translation, and Potential Strategies for Prevention

, 2020
Gwendolyn Pais, Jiajun Liu, Sanja Zepcan, Sean N. Avedissian, Nathaniel J. Rhodes, Kevin J. Downes, Ganesh S. Moorthy, Marc H. Scheetz   +7 more
openalex   +2 more sources

Dietary EPA+DHA Mitigate Hepatic Toxicity and Modify the Oxylipin Profile in an Animal Model of Colorectal Cancer Treated with Chemotherapy [PDF]

, 2022
Md Monirujjaman, Oliver F. Bathe, Vera C. Mazurak   +2 more
openalex   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Exposure to Animal Feces and Human Health: A Systematic Review and Proposed Research Priorities

, 2017
Gauthami Penakalapati, Jenna M. Swarthout, Miranda J. Delahoy, Lydia McAliley, Breanna K. Wodnik, Karen Lévy, Matthew C. Freeman   +6 more
openalex   +1 more source

Transcranial magnetic stimulation in animal models of neurodegeneration

, 2021
Shahid Bashir, Mohammad Uzair, Turki Abualait, Arshad Muhammad, Woo‐Kyoung Yoo, Ali Mir, ReemFahd Bunyan   +6 more
openalex   +1 more source

¿Humanización? Como bichos raros (reseña)

Desde el Jardín de Freud
Reseña: Soler, Colette. ¿Humanización? Medellín: Ediciones de Foros Hispanohablantes del Campo Lacaniano de la IF-EPFCL, 2019. 249 páginas.
Luisa Fernanda Gómez Lozano
doaj   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Disentangling the relative roles of resource acquisition and allocation on animal feed efficiency: insights from a dairy cow model [PDF]

, 2016
Laurence Puillet, Denis Réale, N.C. Friggens   +2 more
openalex   +1 more source

Structure-based discovery of potent WD repeat domain 5 inhibitors that demonstrate efficacy and safety in preclinical animal models

, 2022
Kevin B. Teuscher, Somenath Chowdhury, Kenneth M. Meyers, Jianhua Tian, Jiqing Sai, Mayme Van Meveren, Taylor M. South, John Sensintaffar, Tyson A. Rietz, Soumita Goswami, Jing Wang, Brian C. Grieb, Shelly L. Lorey, Gregory C. Howard, Qi Liu, William Moore, Gordon M. Stott, William P. Tansey, Taekyu Lee, Stephen W. Fesik   +19 more
openalex   +2 more sources