Results 191 to 200 of about 2,235,257 (308)

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Collagen Hydrolysates from Animal By-Products in Topical Cosmetic Formulations. [PDF]

Int J Mol Sci
Egner P, Pavlačková J, Sedlaříková J, Matošková L, Mokrejš P, Janalíková M.   +5 more
europepmc   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Natural Polymer-Based Coatings for Animal-Derived Products: A Review of Applications, Functionality, Characterization, and Challenges. [PDF]

Foods
Vargas-Ramella M, Echegaray N, Campagnol PCB, Lorenzo JM.   +3 more
europepmc   +1 more source

Effects of Plant and Animal Natural Products on Mitophagy. [PDF]

Oxid Med Cell Longev, 2020
Shakeri F, Bianconi V, Pirro M, Sahebkar A.   +3 more
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

A Comprehensive Review on the Valorization of Bioactives from Marine Animal By-Products for Health-Promoting, Biofunctional Cosmetics. [PDF]

Mar Drugs
Papadopoulou SNA, Adamantidi T, Kranas D, Cholidis P, Anastasiadou C, Tsoupras A.   +5 more
europepmc   +1 more source

Ethics views on animal science and animal production [PDF]

Animal Frontiers, 2020
openaire   +3 more sources

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Evaluation of an alkaline hydrolysis method under atmospheric pressure for Category 1 animal by-products. [PDF]

EFSA J
EFSA Panel on Biological Hazards (BIOHAZ), Allende A, Bortolaia V, Bover-Cid S, Dohmen W, Mughini-Gras L, Guillier L, Herman LM, Jacxsens L, Nauta M, Ottoson J, Peixe L, Perez-Rodriguez F, Skandamis P, Suffredini E, De Cesare A, Escamez PF, Nonno R, Kryemadhi K, Ortiz-Pelaez A, Alvarez-Ordóñez A.   +20 more
europepmc   +1 more source