Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Regulatory Implications and Control Measures for Lumpy Skin Disease, Highly Pathogenic Avian Influenza, and Foot-and-Mouth Disease in European Livestock. [PDF]
Baptista C +7 more
europepmc +1 more source
Small RNA pathways in mammalian oocytes
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley +1 more source
Surface electromyography as a non-invasive method for detecting stress-induced changes in gastrointestinal motility in pigs. [PDF]
Csötönyi O +7 more
europepmc +1 more source
Molecular epidemiology of <i>Theileria parva</i> in cattle, factors associated with the positivity in northern Malawi, and efficacy of traditional medicine. [PDF]
Kayira GK +7 more
europepmc +1 more source
Deployment of a herd health package increases production traits and reduces parasite load and disease incidence in sheep and goats in Mali. [PDF]
Zannou OM +6 more
europepmc +1 more source
Brain-Wide Activations Related to Forepaw Force Control Identified by Behaving Mouse FMRI. [PDF]
Jindal V +6 more
europepmc +1 more source
Microrobots for Precision Diagnosis and Treatment in the Digestive System: A Review of Actuation Mechanisms, Structural Design, Preclinical and Translational Applications. [PDF]
Gao Y, Liu F, Li G.
europepmc +1 more source

