Results 61 to 70 of about 12,956,766 (310)

Curcumin alleviates zearalenone-induced liver injury in mice by scavenging reactive oxygen species and inhibiting mitochondrial apoptosis pathway

Ecotoxicology and Environmental Safety
Curcumin (CUR) is a compound extracted from turmeric that has a variety of functions including antioxidant and anti-inflammatory. As an estrogen-like mycotoxin, zearalenone (ZEN) not only attacks the reproductive system, but also has toxic effects on the
Xiaopeng Yang, Hao Zheng, Junlong Niu, Xiaoshuang Chen, Hongfei Li, Zhiyong Rao, Yongpeng Guo, Wei Zhang, Zhixiang Wang   +8 more
doaj   +1 more source

Recent progress of porcine milk components and mammary gland function

Journal of Animal Science and Biotechnology, 2018
As the only nutritional source for newborn piglets, porcine colostrum and milk contain critical nutritional and immunological components including carbohydrates, lipids, and proteins (immunoglobulins).
Shihai Zhang, Fang Chen, Yinzhi Zhang, Yantao Lv, Jinghui Heng, Tian Min, Lilang Li, Wutai Guan   +7 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Molecular characteristics and phylogenetic analysis of pigeon paramyxovirus type 1 isolates from pigeon meat farms in Shanghai (2009–2012)

Scientific Reports
The majority of pigeon paramyxovirus type 1 (PPMV-1) strains are generally non-pathogenic to chickens; however, they can induce severe illness and high mortality rates in pigeons, leading to substantial economic repercussions.
Wenwei Sheng, Kexuan Wang, Yaping Gui, Xinyong Qi, Liping Shen, Yujie Zhang, Congsheng Tang, Xin Li, Jun Tao, Chuangui Cao, Weidong Qian, Jian Liu   +11 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Quantum dot nanobead-based fluorescent immunochromatography test strips for rapid visual detection of echinococcosis

Animal Diseases
Hydatid disease, a neglected zoonotic infection caused by Echinococcus granulosus, remains hyperendemic in pastoral regions with limited resources underresourced veterinary surveillance systems.
Gesang Zhuoma, Gongsang Quzhen, Bianba Yangla, Geshang Yangzong, Chidan Zhuoga, Yuzhen Deji, Suolang Sizhu   +6 more
doaj   +1 more source

Metabolic transition of milk triacylglycerol synthesis in response to varying levels of palmitate in porcine mammary epithelial cells

Genes & Nutrition, 2018
Background Milk in mammals is a key source of lipids for offspring, providing both critical energy and essential fatty acids. For lactating sows, palmitic acid is one of the most abundant fatty acids in milk, providing 10~12% of the suckling pig total ...
Yantao Lv, Shihai Zhang, Wutai Guan, Fang Chen, Yinzhi Zhang, Jun Chen, Yang Liu   +6 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

GLUT1 and lactose synthetase are critical genes for lactose synthesis in lactating sows

Nutrition & Metabolism, 2018
Background Lactose synthesis rate is an important factor in milk production and quality in mammals. Understanding the lactose synthesis mechanism is crucial for the improvement of milk quantity and quality.
Yinzhi Zhang, Shihai Zhang, Wutai Guan, Fang Chen, Lin Cheng, Yantao Lv, Jun Chen   +6 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source