Results 121 to 130 of about 8,583,279 (359)

A Salmonella virulence factor activates the NOD1/NOD2 signaling pathway. [PDF]

, 2011
The invasion-associated type III secretion system (T3SS-1) of Salmonella enterica serotype Typhimurium (S. Typhimurium) activates the transcription factor NF-κB in tissue culture cells and induces inflammatory responses in animal models through unknown ...
Bäumler, Andreas J, Keestra, A Marijke, Kim, Anita, Klein-Douwel, Daisy, Tsolis, Renée M, Winter, Maria G, Winter, Sebastian E, Xavier, Mariana N   +7 more
core   +2 more sources

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Changes in the rumen development, rumen fermentation, and rumen microbiota community in weaned calves during steviol glycosides treatment

Frontiers in Microbiology
Early weaning leads to weaning stress in calves, which hinders healthy growth and development. As an excellent sweetener applied in food, steviol glycosides (STE) has also been shown to exhibit positive biological activity in monogastric animals ...
Kexin Wang, Maocheng Jiang, Yuhang Chen, Yuncheng Huang, Zhiqiang Cheng, Osmond Datsomor, Shakib Mohamed Jama, Liping Zhu, Yajing Li, Guoqi Zhao, Guoqi Zhao, Guoqi Zhao, Miao Lin   +12 more
doaj   +1 more source

Blackfish Lessons on Environmental Sustainability, Food, and Indigenous Culture [PDF]

, 2017
This essay, “Blackfish Lessons on Environmental Sustainability, Food, and Indigenous Culture,” examines Yup’ik interventions into understanding the place of human-nonhuman animal relations in regard to ecological sustainability.
Swensen, Thomas
core  

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Editorial: Songs and Signs: Interdisciplinary Perspectives on Cultural Transmission and Inheritance in Human and Nonhuman Animals

Frontiers in Psychology, 2022
Julia Hyland Bruno, Brian Boyd, David Rothenberg   +2 more
doaj   +1 more source

Halfway between 2D and Animal Models: Are 3D Cultures the Ideal Tool to Study Cancer-Microenvironment Interactions?

International Journal of Molecular Sciences, 2018
An area that has come to be of tremendous interest in tumor research in the last decade is the role of the microenvironment in the biology of neoplastic diseases.
Jessica Hoarau-Véchot, A. Rafii, C. Touboul, J. Pasquier   +3 more
semanticscholar   +1 more source

A bioinformatics screen identifies TCF19 as an aggressiveness‐sustaining gene in prostate cancer

Molecular Oncology, EarlyView.
Gene expression meta‐analysis in multiple prostate cancer patient cohorts identifies Transcription factor 19 (TCF19) as an aggressiveness‐sustaining gene with prognostic potential. TCF19 is a gene repressed by androgen signaling that sustains core cancer‐related processes such as vascular permeability or tumor growth and metastasis.
Amaia Ercilla, Jana R. Crespo, Saioa Garcia‐Longarte, Marta Fidalgo, Sara del Palacio, Natalia Martin‐Martin, Onintza Carlevaris, Ianire Astobiza, Sonia Fernández‐Ruiz, Marc Guiu, Laura Bárcena, Isabel Mendizabal, Ana M. Aransay, Mariona Graupera, Roger R. Gomis, Arkaitz Carracedo   +15 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Advancing animal health and disease research in the lab with three‐dimensional cell culture systems

, 2022
David W. Smith, Daniel R. G. Price, Marc Faber, Ambre F. Chapuis, Tom N. McNeilly   +4 more
openalex   +1 more source