Results 61 to 70 of about 8,583,279 (359)

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

open access: yesFEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz   +5 more
wiley   +1 more source

Molecular characterization of a novel C-type lectin receptors (CD302) in Nile tilapia (Oreochromis niloticus) and its functional analysis in host defense against bacterial infection

open access: yesAquaculture Reports, 2022
C-type lectin receptors (CLRs) are a group of carbohydrate-binding proteins which function by mediating multiple biological events, including adhesion between cells, the turnover of serum glycoproteins, and the innate immune system's reaction to ...
Zhiqiang Zhang   +7 more
doaj   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

The Effect of Colored and White Light on Growth and Phycobiliproteins, Chlorophyll and Carotenoids Content of the Marine Cyanobacteria Phormidium sp. and Cyanothece sp. in Batch Cultures

open access: yesLife, 2022
Two local marine cyanobacteria, Phormidium sp. and Cyanothece sp., were batch-cultured under 18–19.5 °C, at 40 ppt salinity, using white LED light of low (40 μmol photons/m2/s) and high (160 μmol/m2/s) intensity and, additionally, blue, green and red LED
George N. Hotos, Theodoros I. Antoniadis
doaj   +1 more source

Aquaculture Asia, Vol. 8, No. 1, pp.1-58, January-March 2003 [PDF]

open access: yes, 2003
*Table of Contents* Sustainable Aquaculture Fertilization, soil and water quality management in small-scale ponds part II:Soil and water quality management S.

core  

Animal‐cell culture media: History, characteristics, and current issues

open access: yesReproductive Medicine and Biology, 2017
Cell culture technology has spread prolifically within a century, a variety of culture media has been designed. This review goes through the history, characteristics and current issues of animal‐cell culture media.
Tatsuma Yao, Yuta Asayama
semanticscholar   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

open access: yesFEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur   +5 more
wiley   +1 more source

Response of the Ciliates Fabrea salina and Condylostoma sp. to Different Salinities and Microalgal Feeds

open access: yesEcologies, 2022
In the quest of finding local strains of marine ciliates that can be easily cultured under a broad range of salinity and fed with microalgae, Fabrea salina Henneguy, 1890 and Condylostoma sp. Bory de St.
George N. Hotos, Ioanna Touloupi
doaj   +1 more source

Treatment of Ligament Constructs with Exercise-conditioned Serum: A Translational Tissue Engineering Model. [PDF]

open access: yes, 2017
In vitro experiments are essential to understand biological mechanisms; however, the gap between monolayer tissue culture and human physiology is large, and translation of findings is often poor.
Baar, Keith   +2 more
core   +2 more sources

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