Results 151 to 160 of about 1,347,369 (302)

Killing animals [PDF]

open access: yes, 2006
Though not often acknowledged openly, killing represents by far the most common form of human interaction with animals. Humans kill animals for food, for pleasure, to wear, and even as religious acts, yet despite the ubiquity of this killing, analyzing ...

core  

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

“the Animal” After Derrida: Interrogating the Bioethics of Geno-Cide [PDF]

open access: yes, 2013
Bioethics tends to be dominated by discourses concerned with the ethical dimension of medical practice, the organization of medical care, and the integrity of biomedical research involving human subjects and animal testing.
Swazo, Norman
core  

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

An Evolutionary Point of View of Animal Ethics. [PDF]

open access: yesFront Psychol, 2020
Criscuolo F, Sueur C.
europepmc   +1 more source

Research, values, and ethics in organic agriculture - examples from sustainability, precaution, nature quality, and animal welfare [PDF]

open access: yes, 2000
Agricultural systems are characterised by involving both natural and social systems. Organic farming, in particular, has developed as part of a wider organic movement incorporating producers, manufacturers and consumers.
Alrøe, Hugo Fjelsted   +1 more
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