Results 121 to 130 of about 2,061,939 (349)

TEMAS POLÊMICOS E A ARGUMENTAÇÃO DE ESTUDANTES DO CURSO DE CIÊNCIAS BIOLÓGICAS

open access: yesEnsaio Pesquisa em Educação em Ciências
Analisa-se a estrutura e consistência dos argumentos de alunos do curso de Ciências Biológicas quando instigados a defender determinado ponto de vista sobre dois temas "Mercado de Carbono" e "Experimetação Animal".
Daniela Malgarini Perez   +6 more
doaj   +1 more source

Sainfoin – New Data on Anthelmintic Effects and Production in Sheep and Goats [PDF]

open access: yes, 2012
Gastrointestinal nematodes (GIN) are one of the most important problems affecting health and therefore performance and welfare in small ruminant husbandry.
Amsler, Z.   +9 more
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Resting energy metabolism and pulmonary ventilation in growing swine. [PDF]

open access: yes, 1944
Publication authorized February 9, 1944."Animal Husbandry Department and Dairy Department, Missouri Agricultural Experiment Station, and the Bureau of Animal Industry, Agricultural Research Administration, United States Department of Agriculture ...
Brody, Samuel, 1890-1956   +1 more
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Resting energy metabolism and pulmonary ventilation in growing horses. [PDF]

open access: yes, 1943
Publication authorized May 14, 1943."Animal Husbandry Department and Dairy Department, Missouri Agricultural Experiment Station and the Bureau of Animal Industry, Agricultural Research Administration, United States Department of Agriculture, cooperating."
Brody, Samuel, 1890-1956   +2 more
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

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