Results 131 to 140 of about 4,974,799 (302)

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

A program for making completely balanced Latin Square designs employing a systemic method Programa para lograr un balance total en los diseños estadísticos tipo Cuadrado Latino, empleando un método sistémico Programa para lograr um balanceamento total nos delineamentos estadísticos tipo Quadrado Latino, usando um método sistêmico

open access: yesRevista Colombiana de Ciencias Pecuarias, 2010
Animal scientists employ Latin square designs to reduce the required number of animals for detecting statistical differences in animal experiments. Randomization procedures do not balance residual effects that possibly exist in Latin square experiments ...
Beob G Kim, Taemin Kim
doaj  

Active and Passive Mineralization of Bio-Gide® Membranes in Rat Calvaria Defects

open access: yesJournal of Functional Biomaterials
Bio-Gide® is a collagen membrane routinely used in guided bone regeneration. Recent studies have shown that this collagen membrane has osteoconductive properties, meaning that it can support the growth of new bone. However, it has also been observed that
Karol Ali Apaza Alccayhuaman   +7 more
doaj   +1 more source

Cattle feeding investigations: fattening two-year old steers for market; fattening calves for baby beef

open access: yes, 1922
This archival publication may not reflect current scientific knowledge or recommendations. Current information available from University of Minnesota Agricultural Experiment Station: http://www.maes.umn.edu/Peters, W.
Peters, W. H.   +2 more
core  

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Annual report, Agricultural Experiment Station, University of Minnesota, 1893

open access: yes, 1894
1 electronic resource (PDF, xxii pages)University of Minnesota. Agricultural Experiment Station. (1894). Annual report, Agricultural Experiment Station, University of Minnesota, 1893.
University of Arizona. Agricultural Experiment Station.   +1 more
core  

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

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