Results 141 to 150 of about 2,061,939 (349)

Concept for the controlled plane wave exposure for animal experiments using a parabolic reflector [PDF]

, 2005
S. Tejero, S. Schelkshorn, J. Detlefsen
openalex   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

The nematode worm Caenorhabditis elegans as an animal experiment replacement for assessing the virulence of different Salmonella enterica strains. [PDF]

Front Microbiol, 2023
Burkhardt W, Salzinger C, Fischer J, Malorny B, Fischer M, Szabo I.   +5 more
europepmc   +1 more source

Kinematics of hovering hummingbird flight along simulated and natural elevational gradients [PDF]

, 2003
Hovering flight is one of the most energetically demanding forms of animal locomotion. Despite the cost, hummingbirds regularly hover at high elevations, where flight is doubly challenging because of reduced air density and oxygen availability.
Altshuler, Douglas L., Dudley, Robert
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Functional evaluation of pure natural edible Ferment: protective function on ulcerative colitis

Frontiers in Microbiology
PurposeTo investigate the therapeutic efficiency of a novel drink termed “Ferment” in cases of ulcerative colitis (UC) and its influence on the gut microbiota.MethodIn this study, we developed a complex of mixed fruit juice and lactic acid bacteria ...
Yanjun Chen, Shengzhi Ye, Jiaolong Shi, Hao Wang, Guangxu Deng, Guangxian Wang, Shijie Wang, Shijie Wang, Qingbin Yuan, Lunan Yang, Tingyu Mou   +10 more
doaj   +1 more source

Integrated Network Pharmacology, Molecular Docking and Animal Experiment to Explore the Efficacy and Potential Mechanism of Baiyu Decoction Against Ulcerative Colitis by Enema. [PDF]

Drug Des Devel Ther, 2023
Cui Y, Hu J, Li Y, Au R, Fang Y, Cheng C, Xu F, Li W, Wu Y, Zhu L, Shen H.   +10 more
europepmc   +1 more source

Circular 68 [PDF]

, 1989
Livestock rations should be balanced for many parameters including protein, and various minerals, and energy, to ensure that all required nutrients are present in the adequate amounts and proper relationships. Energy content is the primary consideration
Bruce, Leroy Ben, Herlugson, Mary Lou
core  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

A program for making completely balanced Latin Square designs employing a systemic method Programa para lograr un balance total en los diseños estadísticos tipo Cuadrado Latino, empleando un método sistémico Programa para lograr um balanceamento total nos delineamentos estadísticos tipo Quadrado Latino, usando um método sistêmico

Revista Colombiana de Ciencias Pecuarias, 2010
Animal scientists employ Latin square designs to reduce the required number of animals for detecting statistical differences in animal experiments. Randomization procedures do not balance residual effects that possibly exist in Latin square experiments ...
Beob G Kim, Taemin Kim
doaj