Results 101 to 110 of about 377,815 (340)
Frontiers in Immunology, 2017 Protein aggregates have been reported to act as a reservoir that can release biologically active, native form of precursor protein. Keeping this fact into consideration, it is tempting to exploit protein aggregate-based antigen delivery system as a ...
Faraz Ahmad +5 more
doaj +1 more source
The "Big Three" in biocompatibility testing of medical devices: implementation of alternatives to animal experimentation-are we there yet? [PDF]
Front Toxicol, 2023 Kanďárová H, Pôbiš P.
europepmc +1 more source
Animal Experimentation: The Biological Significance of Phospholipase C β1 Gene Mutation in Mouse Sperm in the Acrosome Reaction, Fertilization, and Embryo Development [PDF]
, 2001 DooSeok Choi +7 more
openalex +1 more source
Evidence of the effects of Mycosphaerella leaf spot diseases on fruit quality [PDF]
, 2008 Mycosphaerella leaf spot diseases Sigatoka disease (SD) and Black leaf streak disease (BLSD) are considered as the most severe diseases of bananas for the export market.
Abadie, Catherine +6 more
core
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Automating image analysis by annotating landmarks with deep neural networks [PDF]
, 2017 Image and video analysis is often a crucial step in the study of animal behavior and kinematics. Often these analyses require that the position of one or more animal landmarks are annotated (marked) in numerous images. The process of annotating landmarks
Betke, Margrit +3 more
core +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
How to optimize communication about animal and animal-free research methods
Frontiers in Veterinary ScienceThere is a long-standing debate about experimental non-human animals and animal-free methods in scientific research. Among the various stakeholders involved in the debate are the scientists.
Judith Regina Homberg +7 more
doaj +1 more source